| 1 | Sat 30 Jul 2022 | 190-1 v Cambridge UnitedCambridge United 1-0 Milton Keynes Dons | Sky Bet League One |
| 2 | Sat 6 Aug 2022 | 190-1 v Sheffield WednesdayMilton Keynes Dons 0-1 Sheffield Wednesday | Sky Bet League One |
| 3 | Tue 9 Aug 2022 | 191-0 v Sutton UnitedMilton Keynes Dons 1-0 Sutton United | Carabao Cup First Round |
| 4 | Sat 13 Aug 2022 | 190-3 v Ipswich TownIpswich Town 3-0 Milton Keynes Dons | Sky Bet League One |
| 5 | Tue 16 Aug 2022 | 192-1 v Port ValeMilton Keynes Dons 2-1 Port Vale | Sky Bet League One |
| 6 | Sat 20 Aug 2022 | 191-1 v Accrington StanleyMilton Keynes Dons 1-1 Accrington Stanley | Sky Bet League One |
| 7 | Tue 23 Aug 2022 | 192-0 v WatfordWatford 0-2 Milton Keynes Dons | Carabao Cup Second Round |
| 8 | Sat 27 Aug 2022 | 194-0 v MorecambeMorecambe 0-4 Milton Keynes Dons | Sky Bet League One |
| 9 | Tue 30 Aug 2022 | 191-2 v Cheltenham TownMilton Keynes Dons 1-2 Cheltenham Town | Papa John’s Trophy |
| 10 | Sat 1 Oct 2022 | 192-3 v Peterborough UnitedMilton Keynes Dons 2-3 Peterborough United | Sky Bet League One |
| 11 | Sat 8 Oct 2022 | 191-2 v Shrewsbury TownShrewsbury Town 2-1 Milton Keynes Dons | Sky Bet League One |
| 12 | Tue 11 Oct 2022 | 190-1 v Bristol RoversMilton Keynes Dons 0-1 Bristol Rovers | Sky Bet League One |
| 13 | Sat 15 Oct 2022 | 191-4 v Plymouth ArgyleMilton Keynes Dons 1-4 Plymouth Argyle | Sky Bet League One |
| 14 | Tue 18 Oct 2022 | 192-0 v WalsallWalsall 0-2 Milton Keynes Dons | Papa John’s Trophy Southern Group C |
| 15 | Sat 22 Oct 2022 | 190-1 v Wycombe WanderersMilton Keynes Dons 0-1 Wycombe Wanderers | Sky Bet League One |
| 16 | Tue 25 Oct 2022 | 192-0 v Charlton AthleticCharlton Athletic 0-2 Milton Keynes Dons | Sky Bet League One |
| 17 | Sat 29 Oct 2022 | 190-0 v Cheltenham TownCheltenham Town 0-0 Milton Keynes Dons | Sky Bet League One |
| 18 | Sat 5 Nov 2022 | 196-0 v Taunton TownMilton Keynes Dons 6-0 Taunton Town | Emirates FA Cup First Round |
| 19 | Sat 12 Nov 2022 | 191-3 v Derby CountyMilton Keynes Dons 1-3 Derby County | Sky Bet League One |
| 20 | Sat 19 Nov 2022 | 191-3 v BarnsleyBarnsley 3-1 Milton Keynes Dons | Sky Bet League One |
| 21 | Tue 22 Nov 2022 | 193-1 v Newport CountyMilton Keynes Dons 3-1 Newport County | Papa John’s Trophy Second Round |
| 22 | Sat 26 Nov 2022 | 192-3 v PortsmouthPortsmouth 3-2 Milton Keynes Dons | Emirates FA Cup Second Round |
| 23 | Sat 3 Dec 2022 | 191-1 v Burton AlbionMilton Keynes Dons 1-1 Burton Albion | Sky Bet League One |
| 24 | Sat 10 Dec 2022 | 191-2 v Fleetwood TownMilton Keynes Dons 1-2 Fleetwood Town | Sky Bet League One |
| 25 | Tue 13 Dec 2022 | 191-4 v Bristol RoversBristol Rovers 4-1 Milton Keynes Dons | Papa John’s Trophy Third Round |
| 26 | Sat 17 Dec 2022 | 192-0 v PortsmouthPortsmouth 0-2 Milton Keynes Dons | Sky Bet League One |
| 27 | Tue 20 Dec 2022 | 190-3 v Leicester CityMilton Keynes Dons 0-3 Leicester City | Carabao Cup Fourth Round |
| 28 | Mon 26 Dec 2022 | 191-0 v Forest Green RoversMilton Keynes Dons 1-0 Forest Green Rovers | Sky Bet League One |
| 29 | Thu 29 Dec 2022 | 190-2 v Peterborough UnitedPeterborough United 2-0 Milton Keynes Dons | Sky Bet League One |
| 30 | Sun 1 Jan 2023 | 191-3 v Plymouth ArgylePlymouth Argyle 3-1 Milton Keynes Dons | Sky Bet League One |
| 31 | Sat 14 Jan 2023 | 190-0 v Lincoln CityMilton Keynes Dons 0-0 Lincoln City | Sky Bet League One |
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