| 1 | Sat 6 Aug 2022 | 80-1 v Sheffield WednesdayMilton Keynes Dons 0-1 Sheffield Wednesday | Sky Bet League One |
| 2 | Tue 9 Aug 2022 | 81-0 v Sutton UnitedMilton Keynes Dons 1-0 Sutton United | Carabao Cup First Round |
| 3 | Sat 13 Aug 2022 | 8 0-3 v Ipswich TownIpswich Town 3-0 Milton Keynes Dons | Sky Bet League One |
| 4 | Tue 16 Aug 2022 | 82-1 v Port ValeMilton Keynes Dons 2-1 Port Vale | Sky Bet League One |
| 5 | Sat 20 Aug 2022 | 81-1 v Accrington StanleyMilton Keynes Dons 1-1 Accrington Stanley | Sky Bet League One |
| 6 | Tue 23 Aug 2022 | 82-0 v WatfordWatford 0-2 Milton Keynes Dons | Carabao Cup Second Round |
| 7 | Sat 27 Aug 2022 | 84-0 v MorecambeMorecambe 0-4 Milton Keynes Dons | Sky Bet League One |
| 8 | Tue 30 Aug 2022 | 81-2 v Cheltenham TownMilton Keynes Dons 1-2 Cheltenham Town | Papa John’s Trophy |
| 9 | Sat 1 Oct 2022 | 8 2-3 v Peterborough UnitedMilton Keynes Dons 2-3 Peterborough United | Sky Bet League One |
| 10 | Tue 11 Oct 2022 | 8 0-1 v Bristol RoversMilton Keynes Dons 0-1 Bristol Rovers | Sky Bet League One |
| 11 | Sat 15 Oct 2022 | 8 1-4 v Plymouth ArgyleMilton Keynes Dons 1-4 Plymouth Argyle | Sky Bet League One |
| 12 | Tue 18 Oct 2022 | 82-0 v WalsallWalsall 0-2 Milton Keynes Dons | Papa John’s Trophy Southern Group C |
| 13 | Tue 8 Nov 2022 | 82-0 v MorecambeMilton Keynes Dons 2-0 Morecambe | Carabao Cup Third Round |
| 14 | Tue 22 Nov 2022 | 83-1 v Newport CountyMilton Keynes Dons 3-1 Newport County | Papa John’s Trophy Second Round |
| 15 | Sat 26 Nov 2022 | 82-3 v PortsmouthPortsmouth 3-2 Milton Keynes Dons | Emirates FA Cup Second Round |
| 16 | Sat 10 Dec 2022 | 81-2 v Fleetwood TownMilton Keynes Dons 1-2 Fleetwood Town | Sky Bet League One |
| 17 | Tue 13 Dec 2022 | 81-4 v Bristol RoversBristol Rovers 4-1 Milton Keynes Dons | Papa John’s Trophy Third Round |
| 18 | Sat 17 Dec 2022 | 82-0 v PortsmouthPortsmouth 0-2 Milton Keynes Dons | Sky Bet League One |
| 19 | Thu 29 Dec 2022 | 80-2 v Peterborough UnitedPeterborough United 2-0 Milton Keynes Dons | Sky Bet League One |
| 20 | Sun 1 Jan 2023 | 81-3 v Plymouth ArgylePlymouth Argyle 3-1 Milton Keynes Dons | Sky Bet League One |
| 21 | Sat 14 Jan 2023 | 80-0 v Lincoln CityMilton Keynes Dons 0-0 Lincoln City | Sky Bet League One |
| 22 | Tue 28 Feb 2023 | 81-1 v Lincoln CityLincoln City 1-1 Milton Keynes Dons | Sky Bet League One |
| 23 | Sat 18 Mar 2023 | 81-0 v Accrington StanleyAccrington Stanley 0-1 Milton Keynes Dons | Sky Bet League One |
| 24 | Mon 10 Apr 2023 | 81-1 v Derby CountyDerby County 1-1 Milton Keynes Dons | Sky Bet League One |
| 25 | Sat 15 Apr 2023 | 82-2 v Cheltenham TownMilton Keynes Dons 2-2 Cheltenham Town | Sky Bet League One |
| 26 | Tue 18 Apr 2023 | 80-1 v Charlton AthleticMilton Keynes Dons 0-1 Charlton Athletic | Sky Bet League One |
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