| 1 | Sat 7 Aug 2021 | 142-1 v Bristol RoversMansfield Town 2-1 Bristol Rovers | Sky Bet League Two |
| 2 | Sat 14 Aug 2021 | 14 2-1 v Newport CountyMansfield Town 2-1 Newport County | Sky Bet League Two |
| 3 | Tue 17 Aug 2021 | 14 1-1 v Colchester UnitedColchester United 1-1 Mansfield Town | Sky Bet League Two |
| 4 | Sat 21 Aug 2021 | 142-3 v Bradford CityMansfield Town 2-3 Bradford City | Sky Bet League Two |
| 5 | Sat 29 Jan 2022 | 142-0 v Leyton OrientMansfield Town 2-0 Leyton Orient | Sky Bet League Two |
| 6 | Tue 1 Feb 2022 | 140-0 v Harrogate TownHarrogate Town 0-0 Mansfield Town | Sky Bet League Two |
| 7 | Fri 4 Mar 2022 | 142-1 v Exeter CityMansfield Town 2-1 Exeter City | Sky Bet League Two |
| 8 | Fri 11 Mar 2022 | 142-3 v Tranmere RoversTranmere Rovers 3-2 Mansfield Town | Sky Bet League Two |
| 9 | Tue 15 Mar 2022 | 141-3 v Port ValePort Vale 3-1 Mansfield Town | Sky Bet League Two |
| 10 | Tue 22 Mar 2022 | 141-0 v RochdaleRochdale 0-1 Mansfield Town | Sky Bet League Two |
| 11 | Sat 26 Mar 2022 | 14 2-1 v Oldham AthleticOldham Athletic 1-2 Mansfield Town | Sky Bet League Two |
| 12 | Tue 29 Mar 2022 | 14 2-2 v Hartlepool UnitedHartlepool United 2-2 Mansfield Town | Sky Bet League Two |
| 13 | Tue 5 Apr 2022 | 140-1 v Forest Green RoversForest Green Rovers 1-0 Mansfield Town | Sky Bet League Two |
| 14 | Sat 9 Apr 2022 | 144-0 v Scunthorpe UnitedScunthorpe United 0-4 Mansfield Town | Sky Bet League Two |
| 15 | Fri 15 Apr 2022 | 142-3 v Sutton UnitedMansfield Town 2-3 Sutton United | Sky Bet League Two |
| 16 | Mon 18 Apr 2022 | 140-1 v Carlisle UnitedCarlisle United 1-0 Mansfield Town | Sky Bet League Two |
| 17 | Sat 23 Apr 2022 | 14 2-0 v Crawley TownMansfield Town 2-0 Crawley Town | Sky Bet League Two |
| 18 | Tue 26 Apr 2022 | 14 2-0 v StevenageMansfield Town 2-0 Stevenage | Sky Bet League Two |
| 19 | Mon 2 May 2022 | 142-2 v Salford CitySalford City 2-2 Mansfield Town | Sky Bet League Two |
| 20 | Sat 7 May 2022 | 142-2 v Forest Green RoversMansfield Town 2-2 Forest Green Rovers | Sky Bet League Two |
| 21 | Sat 14 May 2022 | 14 2-1 v Northampton TownMansfield Town 2-1 Northampton Town | Sky Bet League Two Play-off Semi Final |
| 22 | Wed 18 May 2022 | 141-0 v Northampton TownNorthampton Town 0-1 Mansfield Town | Sky Bet League Two Play-off Semi Final |
| 23 | Sat 28 May 2022 | 14 0-3 v Port ValeMansfield Town 0-3 Port Vale | Sky Bet League Two Play-off Final |
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