| 1 | Sat 24 Oct 2020 | 70-0 v ChelseaManchester United 0-0 Chelsea | Premier League |
| 2 | Wed 28 Oct 2020 | 75-0 v RB LeipzigManchester United 5-0 RB Leipzig | UEFA Champions League Group H |
| 3 | Sun 1 Nov 2020 | 7 0-1 v ArsenalManchester United 0-1 Arsenal | Premier League |
| 4 | Wed 4 Nov 2020 | 71-2 v İstanbul Başakşehirİstanbul Başakşehir 2-1 Manchester United | UEFA Champions League Group H |
| 5 | Sat 7 Nov 2020 | 73-1 v EvertonEverton 1-3 Manchester United | Premier League |
| 6 | Sat 21 Nov 2020 | 7 1-0 v West Bromwich AlbionManchester United 1-0 West Bromwich Albion | Premier League |
| 7 | Tue 24 Nov 2020 | 74-1 v İstanbul BaşakşehirManchester United 4-1 İstanbul Başakşehir | UEFA Champions League Group H |
| 8 | Sun 29 Nov 2020 | 73-2 v SouthamptonSouthampton 2-3 Manchester United | Premier League |
| 9 | Wed 2 Dec 2020 | 71-3 v Paris St GermainManchester United 1-3 Paris St Germain | UEFA Champions League Group H |
| 10 | Sat 5 Dec 2020 | 73-1 v West Ham UnitedWest Ham United 1-3 Manchester United | Premier League |
| 11 | Sun 20 Dec 2020 | 76-2 v Leeds UnitedManchester United 6-2 Leeds United | Premier League |
| 12 | Wed 23 Dec 2020 | 72-0 v EvertonEverton 0-2 Manchester United | Carabao Cup Quarter Final |
| 13 | Sat 26 Dec 2020 | 72-2 v Leicester CityLeicester City 2-2 Manchester United | Premier League |
| 14 | Tue 29 Dec 2020 | 71-0 v Wolverhampton WanderersManchester United 1-0 Wolverhampton Wanderers | Premier League |
| 15 | Tue 12 Jan 2021 | 71-0 v BurnleyBurnley 0-1 Manchester United | Premier League |
| 16 | Sun 17 Jan 2021 | 70-0 v LiverpoolLiverpool 0-0 Manchester United | Premier League |
| 17 | Wed 20 Jan 2021 | 72-1 v FulhamFulham 1-2 Manchester United | Premier League |
| 18 | Sun 24 Jan 2021 | 73-2 v LiverpoolManchester United 3-2 Liverpool | Emirates FA Cup Fourth Round |
| 19 | Wed 27 Jan 2021 | 71-2 v Sheffield UnitedManchester United 1-2 Sheffield United | Premier League |
| 20 | Sat 30 Jan 2021 | 70-0 v ArsenalArsenal 0-0 Manchester United | Premier League |
| 21 | Tue 2 Feb 2021 | 79-0 v SouthamptonManchester United 9-0 Southampton | Premier League |
| 22 | Sat 6 Feb 2021 | 73-3 v EvertonManchester United 3-3 Everton | Premier League |
| 23 | Tue 9 Feb 2021 | 71-0 v West Ham UnitedManchester United 1-0 West Ham United | Emirates FA Cup Fifth Round |
| 24 | Sun 14 Feb 2021 | 71-1 v West Bromwich AlbionWest Bromwich Albion 1-1 Manchester United | Premier League |
| 25 | Wed 3 Mar 2021 | 70-0 v Crystal PalaceCrystal Palace 0-0 Manchester United | Premier League |
| 26 | Sun 21 Mar 2021 | 71-3 v Leicester CityLeicester City 3-1 Manchester United | Emirates FA Cup Sixth Round |
| 27 | Sun 4 Apr 2021 | 7 2-1 v Brighton & Hove AlbionManchester United 2-1 Brighton & Hove Albion | Premier League |
| 28 | Thu 8 Apr 2021 | 72-0 v GranadaGranada 0-2 Manchester United | Europa League Quarter Final |
| 29 | Sun 11 Apr 2021 | 7 3-1 v Tottenham HotspurTottenham Hotspur 1-3 Manchester United | Premier League |
| 30 | Thu 15 Apr 2021 | 72-0 v GranadaManchester United 2-0 Granada | Europa League Quarter Final |
| 31 | Sun 18 Apr 2021 | 73-1 v BurnleyManchester United 3-1 Burnley | Premier League |
| 32 | Sun 25 Apr 2021 | 70-0 v Leeds UnitedLeeds United 0-0 Manchester United | Premier League |
| 33 | Thu 29 Apr 2021 | 76-2 v RomaManchester United 6-2 Roma | Europa League Semi Final |
| 34 | Thu 6 May 2021 | 7 2-3 v RomaRoma 3-2 Manchester United | Europa League Semi Final |
| 35 | Sun 9 May 2021 | 73-1 v Aston VillaAston Villa 1-3 Manchester United | Premier League |
| 36 | Tue 11 May 2021 | 71-2 v Leicester CityManchester United 1-2 Leicester City | Premier League |
| 37 | Thu 13 May 2021 | 7 2-4 v LiverpoolManchester United 2-4 Liverpool | Premier League |
| 38 | Tue 18 May 2021 | 71-1 v FulhamManchester United 1-1 Fulham | Premier League |
| 39 | Wed 26 May 2021 | 7 1-1 v VillarrealVillarreal 1-1 Manchester United | Europa League Final |
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