| 1 | Sun 5 Aug 2012 | 50-0 v ValerengaValerenga 0-0 Manchester United | Friendly |
| 2 | Wed 8 Aug 2012 | 50-0 v BarcelonaBarcelona 0-0 Manchester United | Friendly |
| 3 | Sun 2 Sep 2012 | 53-2 v SouthamptonSouthampton 2-3 Manchester United | Barclays Premier League |
| 4 | Sat 15 Sep 2012 | 54-0 v Wigan AthleticManchester United 4-0 Wigan Athletic | Barclays Premier League |
| 5 | Sun 23 Sep 2012 | 52-1 v LiverpoolLiverpool 1-2 Manchester United | Barclays Premier League |
| 6 | Sat 29 Sep 2012 | 52-3 v Tottenham HotspurManchester United 2-3 Tottenham Hotspur | Barclays Premier League |
| 7 | Tue 2 Oct 2012 | 52-1 v CFR Cluj-NapocaCFR Cluj-Napoca 1-2 Manchester United | UEFA Champions League Group H |
| 8 | Sun 7 Oct 2012 | 53-0 v Newcastle UnitedNewcastle United 0-3 Manchester United | Barclays Premier League |
| 9 | Sat 20 Oct 2012 | 54-2 v Stoke CityManchester United 4-2 Stoke City | Barclays Premier League |
| 10 | Sun 28 Oct 2012 | 53-2 v ChelseaChelsea 2-3 Manchester United | Barclays Premier League |
| 11 | Sat 3 Nov 2012 | 52-1 v ArsenalManchester United 2-1 Arsenal | Barclays Premier League |
| 12 | Wed 7 Nov 2012 | 53-1 v BragaBraga 1-3 Manchester United | UEFA Champions League Group H |
| 13 | Sat 10 Nov 2012 | 53-2 v Aston VillaAston Villa 2-3 Manchester United | Barclays Premier League |
| 14 | Sat 17 Nov 2012 | 50-1 v Norwich CityNorwich City 1-0 Manchester United | Barclays Premier League |
| 15 | Sat 24 Nov 2012 | 53-1 v Queens Park RangersManchester United 3-1 Queens Park Rangers | Barclays Premier League |
| 16 | Sat 1 Dec 2012 | 54-3 v ReadingReading 3-4 Manchester United | Barclays Premier League |
| 17 | Sun 9 Dec 2012 | 53-2 v Manchester CityManchester City 2-3 Manchester United | Barclays Premier League |
| 18 | Sat 15 Dec 2012 | 53-1 v SunderlandManchester United 3-1 Sunderland | Barclays Premier League |
| 19 | Wed 26 Dec 2012 | 54-3 v Newcastle UnitedManchester United 4-3 Newcastle United | Barclays Premier League |
| 20 | Tue 1 Jan 2013 | 54-0 v Wigan AthleticWigan Athletic 0-4 Manchester United | Barclays Premier League |
| 21 | Sun 13 Jan 2013 | 52-1 v LiverpoolManchester United 2-1 Liverpool | Barclays Premier League |
| 22 | Sun 20 Jan 2013 | 51-1 v Tottenham HotspurTottenham Hotspur 1-1 Manchester United | Barclays Premier League |
| 23 | Wed 30 Jan 2013 | 52-1 v SouthamptonManchester United 2-1 Southampton | Barclays Premier League |
| 24 | Sat 2 Feb 2013 | 51-0 v FulhamFulham 0-1 Manchester United | Barclays Premier League |
| 25 | Sun 10 Feb 2013 | 52-0 v EvertonManchester United 2-0 Everton | Barclays Premier League |
| 26 | Wed 13 Feb 2013 | 51-1 v Real MadridReal Madrid 1-1 Manchester United | UEFA Champions League First Knockout Round |
| 27 | Sat 23 Feb 2013 | 52-0 v Queens Park RangersQueens Park Rangers 0-2 Manchester United | Barclays Premier League |
| 28 | Tue 5 Mar 2013 | 51-2 v Real MadridManchester United 1-2 Real Madrid | UEFA Champions League First Knockout Round |
| 29 | Sun 10 Mar 2013 | 52-2 v ChelseaManchester United 2-2 Chelsea | FA Cup with Budweiser Quarter Final |
| 30 | Sat 16 Mar 2013 | 51-0 v ReadingManchester United 1-0 Reading | Barclays Premier League |
| 31 | Mon 1 Apr 2013 | 50-1 v ChelseaChelsea 1-0 Manchester United | FA Cup with Budweiser Quarter Final |
| 32 | Mon 8 Apr 2013 | 51-2 v Manchester CityManchester United 1-2 Manchester City | Barclays Premier League |
| 33 | Sun 14 Apr 2013 | 52-0 v Stoke CityStoke City 0-2 Manchester United | Barclays Premier League |
| 34 | Wed 17 Apr 2013 | 52-2 v West Ham UnitedWest Ham United 2-2 Manchester United | Barclays Premier League |
| 35 | Sun 28 Apr 2013 | 51-1 v ArsenalArsenal 1-1 Manchester United | Barclays Premier League |
| 36 | Sun 12 May 2013 | 52-1 v Swansea CityManchester United 2-1 Swansea City | Barclays Premier League |
| 37 | Sun 19 May 2013 | 55-5 v West Bromwich AlbionWest Bromwich Albion 5-5 Manchester United | Barclays Premier League |
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