| 1 | Wed 18 Jun | 42-0 v Wydad ACManchester City 2-0 Wydad AC | Club World Cup Group G |
| 2 | Thu 26 Jun | 45-2 v JuventusJuventus 2-5 Manchester City | Club World Cup Group G |
| 3 | Tue 1 Jul | 43-4 v Al HilalManchester City 3-4 Al Hilal | Club World Cup |
| 4 | Sat 16 Aug | 4 4-0 v Wolverhampton WanderersWolverhampton Wanderers 0-4 Manchester City | Premier League |
| 5 | Sat 23 Aug | 40-2 v Tottenham HotspurManchester City 0-2 Tottenham Hotspur | Premier League |
| 6 | Sun 31 Aug | 41-2 v Brighton & Hove AlbionBrighton & Hove Albion 2-1 Manchester City | Premier League |
| 7 | Sun 14 Sep | 43-0 v Manchester UnitedManchester City 3-0 Manchester United | Premier League |
| 8 | Thu 18 Sep | 42-0 v NapoliManchester City 2-0 Napoli | UEFA Champions League Matchday 1 |
| 9 | Sun 21 Sep | 41-1 v ArsenalArsenal 1-1 Manchester City | Premier League |
| 10 | Wed 24 Sep | 42-0 v Huddersfield TownHuddersfield Town 0-2 Manchester City | Carabao Cup Third Round |
| 11 | Sat 27 Sep | 45-1 v BurnleyManchester City 5-1 Burnley | Premier League |
| 12 | Wed 1 Oct | 42-2 v MonacoMonaco 2-2 Manchester City | UEFA Champions League Matchday 2 |
| 13 | Sun 5 Oct | 41-0 v BrentfordBrentford 0-1 Manchester City | Premier League |
| 14 | Sat 18 Oct | 42-0 v EvertonManchester City 2-0 Everton | Premier League |
| 15 | Tue 21 Oct | 42-0 v VillarrealVillarreal 0-2 Manchester City | UEFA Champions League Matchday 3 |
| 16 | Sun 26 Oct | 4 0-1 v Aston VillaAston Villa 1-0 Manchester City | Premier League |
| 17 | Sun 2 Nov | 43-1 v AFC BournemouthManchester City 3-1 AFC Bournemouth | Premier League |
| 18 | Wed 5 Nov | 44-1 v Borussia DortmundManchester City 4-1 Borussia Dortmund | UEFA Champions League Matchday 4 |
| 19 | Sat 22 Nov | 41-2 v Newcastle UnitedNewcastle United 2-1 Manchester City | Premier League |
| 20 | Tue 25 Nov | 40-2 v Bayer LeverkusenManchester City 0-2 Bayer Leverkusen | UEFA Champions League Matchday 5 |
| 21 | Sat 29 Nov | 43-2 v Leeds UnitedManchester City 3-2 Leeds United | Premier League |
| 22 | Tue 2 Dec | 45-4 v FulhamFulham 4-5 Manchester City | Premier League |
| 23 | Sat 6 Dec | 43-0 v SunderlandManchester City 3-0 Sunderland | Premier League |
| 24 | Wed 10 Dec | 42-1 v Real MadridReal Madrid 1-2 Manchester City | UEFA Champions League Matchday 6 |
| 25 | Sun 14 Dec | 43-0 v Crystal PalaceCrystal Palace 0-3 Manchester City | Premier League |
| 26 | Wed 17 Dec | 42-0 v BrentfordManchester City 2-0 Brentford | Carabao Cup Quarter Final |
| 27 | Sat 20 Dec | 43-0 v West Ham UnitedManchester City 3-0 West Ham United | Premier League |
| 28 | Sat 27 Dec | 42-1 v Nottingham ForestNottingham Forest 1-2 Manchester City | Premier League |
| 29 | Thu 1 Jan | 40-0 v SunderlandSunderland 0-0 Manchester City | Premier League |
| 30 | Sun 4 Jan | 41-1 v ChelseaManchester City 1-1 Chelsea | Premier League |
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