| 1 | Mon 10 Aug 2015 | 33-0 v West Bromwich AlbionWest Bromwich Albion 0-3 Manchester City | Barclays Premier League |
| 2 | Sun 16 Aug 2015 | 33-0 v ChelseaManchester City 3-0 Chelsea | Barclays Premier League |
| 3 | Sun 23 Aug 2015 | 32-0 v EvertonEverton 0-2 Manchester City | Barclays Premier League |
| 4 | Sat 29 Aug 2015 | 32-0 v WatfordManchester City 2-0 Watford | Barclays Premier League |
| 5 | Sat 12 Sep 2015 | 31-0 v Crystal PalaceCrystal Palace 0-1 Manchester City | Barclays Premier League |
| 6 | Tue 15 Sep 2015 | 31-2 v JuventusManchester City 1-2 Juventus | UEFA Champions League Group D |
| 7 | Sat 19 Sep 2015 | 31-2 v West Ham UnitedManchester City 1-2 West Ham United | Barclays Premier League |
| 8 | Tue 22 Sep 2015 | 34-1 v SunderlandSunderland 1-4 Manchester City | Capital One Cup Third Round |
| 9 | Sat 26 Sep 2015 | 31-4 v Tottenham HotspurTottenham Hotspur 4-1 Manchester City | Barclays Premier League |
| 10 | Wed 30 Sep 2015 | 32-1 v Borussia MonchengladbachBorussia Monchengladbach 1-2 Manchester City | UEFA Champions League Group D |
| 11 | Sat 17 Oct 2015 | 35-1 v AFC BournemouthManchester City 5-1 AFC Bournemouth | Barclays Premier League |
| 12 | Wed 21 Oct 2015 | 32-1 v SevillaManchester City 2-1 Sevilla | UEFA Champions League Group D |
| 13 | Sun 25 Oct 2015 | 30-0 v Manchester UnitedManchester United 0-0 Manchester City | Barclays Premier League |
| 14 | Wed 28 Oct 2015 | 35-1 v Crystal PalaceManchester City 5-1 Crystal Palace | Capital One Cup Fourth Round |
| 15 | Sat 31 Oct 2015 | 32-1 v Norwich CityManchester City 2-1 Norwich City | Barclays Premier League |
| 16 | Tue 3 Nov 2015 | 33-1 v SevillaSevilla 1-3 Manchester City | UEFA Champions League Group D |
| 17 | Sun 8 Nov 2015 | 30-0 v Aston VillaAston Villa 0-0 Manchester City | Barclays Premier League |
| 18 | Sat 21 Nov 2015 | 31-4 v LiverpoolManchester City 1-4 Liverpool | Barclays Premier League |
| 19 | Wed 25 Nov 2015 | 30-1 v JuventusJuventus 1-0 Manchester City | UEFA Champions League Group D |
| 20 | Sat 28 Nov 2015 | 33-1 v SouthamptonManchester City 3-1 Southampton | Barclays Premier League |
| 21 | Tue 1 Dec 2015 | 34-1 v Hull CityManchester City 4-1 Hull City | Capital One Cup Quarter Final |
| 22 | Sat 5 Dec 2015 | 30-2 v Stoke CityStoke City 2-0 Manchester City | Barclays Premier League |
| 23 | Tue 8 Dec 2015 | 34-2 v Borussia MonchengladbachManchester City 4-2 Borussia Monchengladbach | UEFA Champions League Group D |
| 24 | Sat 12 Dec 2015 | 32-1 v Swansea CityManchester City 2-1 Swansea City | Barclays Premier League |
| 25 | Mon 21 Dec 2015 | 31-2 v ArsenalArsenal 2-1 Manchester City | Barclays Premier League |
| 26 | Sat 26 Dec 2015 | 34-1 v SunderlandManchester City 4-1 Sunderland | Barclays Premier League |
| 27 | Tue 29 Dec 2015 | 30-0 v Leicester CityLeicester City 0-0 Manchester City | Barclays Premier League |
| 28 | Sat 2 Jan 2016 | 32-1 v WatfordWatford 1-2 Manchester City | Barclays Premier League |
| 29 | Wed 6 Jan 2016 | 31-2 v EvertonEverton 2-1 Manchester City | Capital One Cup Semi Final |
| 30 | Wed 13 Jan 2016 | 30-0 v EvertonManchester City 0-0 Everton | Barclays Premier League |
| 31 | Sat 23 Jan 2016 | 32-2 v West Ham UnitedWest Ham United 2-2 Manchester City | Barclays Premier League |
| 32 | Sat 30 Jan 2016 | 34-0 v Aston VillaAston Villa 0-4 Manchester City | Emirates FA Cup Fourth Round |
| 33 | Tue 2 Feb 2016 | 31-0 v SunderlandSunderland 0-1 Manchester City | Barclays Premier League |
| 34 | Wed 24 Feb 2016 | 33-1 v Dynamo KievDynamo Kiev 1-3 Manchester City | UEFA Champions League First Knockout Round |
| 35 | Sun 28 Feb 2016 | 31-1 v LiverpoolLiverpool 1-1 Manchester City | Capital One Cup Final |
| 36 | Sat 5 Mar 2016 | 34-0 v Aston VillaManchester City 4-0 Aston Villa | Barclays Premier League |
| 37 | Sat 12 Mar 2016 | 30-0 v Norwich CityNorwich City 0-0 Manchester City | Barclays Premier League |
| 38 | Sun 20 Mar 2016 | 30-1 v Manchester UnitedManchester City 0-1 Manchester United | Barclays Premier League |
| 39 | Wed 6 Apr 2016 | 32-2 v Paris St GermainParis St Germain 2-2 Manchester City | UEFA Champions League Quarter Final |
| 40 | Tue 12 Apr 2016 | 31-0 v Paris St GermainManchester City 1-0 Paris St Germain | UEFA Champions League Quarter Final |
| 41 | Sat 16 Apr 2016 | 33-0 v ChelseaChelsea 0-3 Manchester City | Barclays Premier League |
| 42 | Tue 26 Apr 2016 | 30-0 v Real MadridManchester City 0-0 Real Madrid | UEFA Champions League Semi Final |
| 43 | Wed 4 May 2016 | 30-1 v Real MadridReal Madrid 1-0 Manchester City | UEFA Champions League Semi Final |
| 44 | Sun 8 May 2016 | 32-2 v ArsenalManchester City 2-2 Arsenal | Barclays Premier League |
| 45 | Sun 15 May 2016 | 31-1 v Swansea CitySwansea City 1-1 Manchester City | Barclays Premier League |
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