| 1 | Sat 21 Aug 2021 | 161-0 v AlavésAlavés 0-1 Mallorca | Spanish La Liga |
| 2 | Fri 27 Aug 2021 | 161-0 v EspanyolMallorca 1-0 Espanyol | Spanish La Liga |
| 3 | Sat 11 Sep 2021 | 160-2 v Athletic BilbaoAthletic Bilbao 2-0 Mallorca | Spanish La Liga |
| 4 | Sun 19 Sep 2021 | 160-0 v VillarrealMallorca 0-0 Villarreal | Spanish La Liga |
| 5 | Wed 22 Sep 2021 | 161-6 v Real MadridReal Madrid 6-1 Mallorca | Spanish La Liga |
| 6 | Sat 2 Oct 2021 | 161-0 v LevanteMallorca 1-0 Levante | Spanish La Liga |
| 7 | Sat 16 Oct 2021 | 16 0-1 v Real SociedadReal Sociedad 1-0 Mallorca | Spanish La Liga |
| 8 | Sat 23 Oct 2021 | 16 2-2 v ValenciaValencia 2-2 Mallorca | Spanish La Liga |
| 9 | Sun 31 Oct 2021 | 161-1 v CádizCádiz 1-1 Mallorca | Spanish La Liga |
| 10 | Mon 22 Nov 2021 | 161-3 v Rayo VallecanoRayo Vallecano 3-1 Mallorca | Spanish La Liga |
| 11 | Sat 4 Dec 2021 | 162-1 v Atlético MadridAtlético Madrid 1-2 Mallorca | Spanish La Liga |
| 12 | Fri 10 Dec 2021 | 160-0 v Celta VigoMallorca 0-0 Celta Vigo | Spanish La Liga |
| 13 | Sun 2 Jan 2022 | 160-1 v BarcelonaMallorca 0-1 Barcelona | Spanish La Liga |
| 14 | Sat 8 Jan 2022 | 160-2 v LevanteLevante 2-0 Mallorca | Spanish La Liga |
| 15 | Sat 22 Jan 2022 | 160-3 v VillarrealVillarreal 3-0 Mallorca | Spanish La Liga |
| 16 | Sat 5 Feb 2022 | 162-1 v CádizMallorca 2-1 Cádiz | Spanish La Liga |
| 17 | Mon 14 Feb 2022 | 163-2 v Athletic BilbaoMallorca 3-2 Athletic Bilbao | Spanish La Liga |
| 18 | Sun 20 Feb 2022 | 16 1-2 v Real BetisReal Betis 2-1 Mallorca | Spanish La Liga |
| 19 | Sun 6 Mar 2022 | 16 3-4 v Celta VigoCelta Vigo 4-3 Mallorca | Spanish La Liga |
| 20 | Sat 2 Apr 2022 | 160-1 v GetafeGetafe 1-0 Mallorca | Spanish La Liga |
| 21 | Sat 9 Apr 2022 | 161-0 v Atlético MadridMallorca 1-0 Atlético Madrid | Spanish La Liga |
| 22 | Tue 19 Apr 2022 | 162-1 v AlavésMallorca 2-1 Alavés | Spanish La Liga |
| 23 | Sun 1 May 2022 | 161-2 v BarcelonaBarcelona 2-1 Mallorca | Spanish La Liga |
| 24 | Wed 11 May 2022 | 160-0 v SevillaSevilla 0-0 Mallorca | Spanish La Liga |
| 25 | Sun 15 May 2022 | 162-1 v Rayo VallecanoMallorca 2-1 Rayo Vallecano | Spanish La Liga |
| 26 | Sun 22 May 2022 | 162-0 v OsasunaOsasuna 0-2 Mallorca | Spanish La Liga |
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