| 1 | Sat 14 Aug 2021 | 31-1 v Real BetisMallorca 1-1 Real Betis | Spanish La Liga |
| 2 | Sat 21 Aug 2021 | 31-0 v AlavésAlavés 0-1 Mallorca | Spanish La Liga |
| 3 | Fri 27 Aug 2021 | 3 1-0 v EspanyolMallorca 1-0 Espanyol | Spanish La Liga |
| 4 | Sat 11 Sep 2021 | 30-2 v Athletic BilbaoAthletic Bilbao 2-0 Mallorca | Spanish La Liga |
| 5 | Sun 19 Sep 2021 | 30-0 v VillarrealMallorca 0-0 Villarreal | Spanish La Liga |
| 6 | Wed 22 Sep 2021 | 31-6 v Real MadridReal Madrid 6-1 Mallorca | Spanish La Liga |
| 7 | Sun 26 Sep 2021 | 32-3 v OsasunaMallorca 2-3 Osasuna | Spanish La Liga |
| 8 | Sat 2 Oct 2021 | 31-0 v LevanteMallorca 1-0 Levante | Spanish La Liga |
| 9 | Sat 16 Oct 2021 | 30-1 v Real SociedadReal Sociedad 1-0 Mallorca | Spanish La Liga |
| 10 | Sat 23 Oct 2021 | 3 2-2 v ValenciaValencia 2-2 Mallorca | Spanish La Liga |
| 11 | Wed 27 Oct 2021 | 3 1-1 v SevillaMallorca 1-1 Sevilla | Spanish La Liga |
| 12 | Sun 31 Oct 2021 | 31-1 v CádizCádiz 1-1 Mallorca | Spanish La Liga |
| 13 | Mon 22 Nov 2021 | 3 1-3 v Rayo VallecanoRayo Vallecano 3-1 Mallorca | Spanish La Liga |
| 14 | Sun 19 Dec 2021 | 31-4 v GranadaGranada 4-1 Mallorca | Spanish La Liga |
| 15 | Sat 8 Jan 2022 | 30-2 v LevanteLevante 2-0 Mallorca | Spanish La Liga |
| 16 | Sat 5 Feb 2022 | 32-1 v CádizMallorca 2-1 Cádiz | Spanish La Liga |
| 17 | Mon 14 Feb 2022 | 3 3-2 v Athletic BilbaoMallorca 3-2 Athletic Bilbao | Spanish La Liga |
| 18 | Wed 2 Mar 2022 | 30-2 v Real SociedadMallorca 0-2 Real Sociedad | Spanish La Liga |
| 19 | Mon 14 Mar 2022 | 30-3 v Real MadridMallorca 0-3 Real Madrid | Spanish La Liga |
| 20 | Sat 2 Apr 2022 | 30-1 v GetafeGetafe 1-0 Mallorca | Spanish La Liga |
| 21 | Sat 9 Apr 2022 | 31-0 v Atlético MadridMallorca 1-0 Atlético Madrid | Spanish La Liga |
| 22 | Sat 16 Apr 2022 | 3 0-3 v ElcheElche 3-0 Mallorca | Spanish La Liga |
| 23 | Tue 19 Apr 2022 | 32-1 v AlavésMallorca 2-1 Alavés | Spanish La Liga |
| 24 | Sun 1 May 2022 | 31-2 v BarcelonaBarcelona 2-1 Mallorca | Spanish La Liga |
| 25 | Sat 7 May 2022 | 32-6 v GranadaMallorca 2-6 Granada | Spanish La Liga |
| 26 | Wed 11 May 2022 | 3 0-0 v SevillaSevilla 0-0 Mallorca | Spanish La Liga |
| 27 | Sun 15 May 2022 | 32-1 v Rayo VallecanoMallorca 2-1 Rayo Vallecano | Spanish La Liga |
| 28 | Sun 22 May 2022 | 32-0 v OsasunaOsasuna 0-2 Mallorca | Spanish La Liga |
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