| 1 | Thu 28 Aug | 244-1 v RosenborgMainz 05 4-1 Rosenborg | UEFA Europa Conference League |
| 2 | Sat 13 Sep | 240-1 v RB LeipzigMainz 05 0-1 RB Leipzig | German Bundesliga |
| 3 | Thu 23 Oct | 241-0 v Zrinjski MostarMainz 05 1-0 Zrinjski Mostar | UEFA Europa Conference League Matchday 2 |
| 4 | Thu 6 Nov | 242-1 v FiorentinaMainz 05 2-1 Fiorentina | UEFA Europa Conference League Matchday 3 |
| 5 | Sun 9 Nov | 240-1 v Eintracht FrankfurtEintracht Frankfurt 1-0 Mainz 05 | German Bundesliga |
| 6 | Fri 21 Nov | 241-1 v TSG HoffenheimMainz 05 1-1 TSG Hoffenheim | German Bundesliga |
| 7 | Sun 30 Nov | 24 0-4 v SC FreiburgSC Freiburg 4-0 Mainz 05 | German Bundesliga |
| 8 | Fri 5 Dec | 240-1 v Borussia MönchengladbachMainz 05 0-1 Borussia Mönchengladbach | German Bundesliga |
| 9 | Thu 11 Dec | 24 1-1 v Lech PoznańLech Poznań 1-1 Mainz 05 | UEFA Europa Conference League Matchday 5 |
| 10 | Sun 14 Dec | 242-2 v Bayern MunichBayern Munich 2-2 Mainz 05 | German Bundesliga |
| 11 | Thu 12 Mar | 240-0 v Sigma OlomoucSigma Olomouc 0-0 Mainz 05 | UEFA Europa Conference League Round of 16 |
| 12 | Sun 15 Mar | 242-0 v Werder BremenWerder Bremen 0-2 Mainz 05 | German Bundesliga |
| 13 | Thu 19 Mar | 242-0 v Sigma OlomoucMainz 05 2-0 Sigma Olomouc | UEFA Europa Conference League Round of 16 |
| 14 | Sun 22 Mar | 242-1 v Eintracht FrankfurtMainz 05 2-1 Eintracht Frankfurt | German Bundesliga |
| 15 | Sat 4 Apr | 242-1 v TSG HoffenheimTSG Hoffenheim 1-2 Mainz 05 | German Bundesliga |
| 16 | Thu 9 Apr | 242-0 v StrasbourgMainz 05 2-0 Strasbourg | UEFA Europa Conference League Quarter Final |
| 17 | Sun 12 Apr | 240-1 v SC FreiburgMainz 05 0-1 SC Freiburg | German Bundesliga |
| 18 | Thu 16 Apr | 240-4 v StrasbourgStrasbourg 4-0 Mainz 05 | UEFA Europa Conference League Quarter Final |
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