| 1 | Sun 24 Aug | 300-1 v 1 FC KölnMainz 05 0-1 1 FC Köln | German Bundesliga |
| 2 | Thu 28 Aug | 304-1 v RosenborgMainz 05 4-1 Rosenborg | UEFA Europa Conference League |
| 3 | Sat 13 Sep | 300-1 v RB LeipzigMainz 05 0-1 RB Leipzig | German Bundesliga |
| 4 | Sat 20 Sep | 304-1 v FC AugsburgFC Augsburg 1-4 Mainz 05 | German Bundesliga |
| 5 | Sat 27 Sep | 300-2 v Borussia DortmundMainz 05 0-2 Borussia Dortmund | German Bundesliga |
| 6 | Thu 2 Oct | 301-0 v Omonia NicosiaOmonia Nicosia 0-1 Mainz 05 | UEFA Europa Conference League Matchday 1 |
| 7 | Thu 23 Oct | 301-0 v Zrinjski MostarMainz 05 1-0 Zrinjski Mostar | UEFA Europa Conference League Matchday 2 |
| 8 | Sun 26 Oct | 301-2 v VfB StuttgartVfB Stuttgart 2-1 Mainz 05 | German Bundesliga |
| 9 | Sat 1 Nov | 301-1 v Werder BremenMainz 05 1-1 Werder Bremen | German Bundesliga |
| 10 | Thu 6 Nov | 302-1 v FiorentinaMainz 05 2-1 Fiorentina | UEFA Europa Conference League Matchday 3 |
| 11 | Sun 9 Nov | 30 0-1 v Eintracht FrankfurtEintracht Frankfurt 1-0 Mainz 05 | German Bundesliga |
| 12 | Fri 21 Nov | 30 1-1 v TSG HoffenheimMainz 05 1-1 TSG Hoffenheim | German Bundesliga |
| 13 | Thu 27 Nov | 300-1 v CS Universitatea CraiovaCS Universitatea Craiova 1-0 Mainz 05 | UEFA Europa Conference League Matchday 4 |
| 14 | Fri 5 Dec | 300-1 v Borussia MönchengladbachMainz 05 0-1 Borussia Mönchengladbach | German Bundesliga |
| 15 | Thu 11 Dec | 301-1 v Lech PoznańLech Poznań 1-1 Mainz 05 | UEFA Europa Conference League Matchday 5 |
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