| 1 | Thu 21 Aug | 21-2 v RosenborgRosenborg 2-1 Mainz 05 | UEFA Europa Conference League |
| 2 | Sun 24 Aug | 20-1 v 1 FC KölnMainz 05 0-1 1 FC Köln | German Bundesliga |
| 3 | Thu 28 Aug | 24-1 v RosenborgMainz 05 4-1 Rosenborg | UEFA Europa Conference League |
| 4 | Sun 31 Aug | 21-1 v VfL WolfsburgVfL Wolfsburg 1-1 Mainz 05 | German Bundesliga |
| 5 | Sat 13 Sep | 20-1 v RB LeipzigMainz 05 0-1 RB Leipzig | German Bundesliga |
| 6 | Sat 20 Sep | 24-1 v FC AugsburgFC Augsburg 1-4 Mainz 05 | German Bundesliga |
| 7 | Sat 27 Sep | 20-2 v Borussia DortmundMainz 05 0-2 Borussia Dortmund | German Bundesliga |
| 8 | Thu 2 Oct | 21-0 v Omonia NicosiaOmonia Nicosia 0-1 Mainz 05 | UEFA Europa Conference League Matchday 1 |
| 9 | Sun 5 Oct | 20-4 v Hamburger SVHamburger SV 4-0 Mainz 05 | German Bundesliga |
| 10 | Sat 18 Oct | 23-4 v Bayer LeverkusenMainz 05 3-4 Bayer Leverkusen | German Bundesliga |
| 11 | Thu 23 Oct | 21-0 v Zrinjski MostarMainz 05 1-0 Zrinjski Mostar | UEFA Europa Conference League Matchday 2 |
| 12 | Sun 26 Oct | 2 1-2 v VfB StuttgartVfB Stuttgart 2-1 Mainz 05 | German Bundesliga |
| 13 | Sat 1 Nov | 21-1 v Werder BremenMainz 05 1-1 Werder Bremen | German Bundesliga |
| 14 | Thu 6 Nov | 22-1 v FiorentinaMainz 05 2-1 Fiorentina | UEFA Europa Conference League Matchday 3 |
| 15 | Sun 9 Nov | 2 0-1 v Eintracht FrankfurtEintracht Frankfurt 1-0 Mainz 05 | German Bundesliga |
| 16 | Fri 21 Nov | 2 1-1 v TSG HoffenheimMainz 05 1-1 TSG Hoffenheim | German Bundesliga |
| 17 | Sun 30 Nov | 20-4 v SC FreiburgSC Freiburg 4-0 Mainz 05 | German Bundesliga |
| 18 | Fri 5 Dec | 20-1 v Borussia MönchengladbachMainz 05 0-1 Borussia Mönchengladbach | German Bundesliga |
Football Web Pages