| 1 | Sat 20 Sep | 211-4 v Mainz 05FC Augsburg 1-4 Mainz 05 | German Bundesliga |
| 2 | Sat 10 Jan | 202-2 v Union BerlinUnion Berlin 2-2 Mainz 05 | German Bundesliga |
| 3 | Tue 13 Jan | 202-1 v 1 FC HeidenheimMainz 05 2-1 1 FC Heidenheim | German Bundesliga |
| 4 | Sat 17 Jan | 20 1-2 v 1 FC Köln1 FC Köln 2-1 Mainz 05 | German Bundesliga |
| 5 | Sat 24 Jan | 203-1 v VfL WolfsburgMainz 05 3-1 VfL Wolfsburg | German Bundesliga |
| 6 | Sat 31 Jan | 202-1 v RB LeipzigRB Leipzig 1-2 Mainz 05 | German Bundesliga |
| 7 | Sat 7 Feb | 202-0 v FC AugsburgMainz 05 2-0 FC Augsburg | German Bundesliga |
| 8 | Fri 13 Feb | 200-4 v Borussia DortmundBorussia Dortmund 4-0 Mainz 05 | German Bundesliga |
| 9 | Fri 20 Feb | 201-1 v Hamburger SVMainz 05 1-1 Hamburger SV | German Bundesliga |
| 10 | Sat 28 Feb | 201-1 v Bayer LeverkusenBayer Leverkusen 1-1 Mainz 05 | German Bundesliga |
| 11 | Sat 7 Mar | 202-2 v VfB StuttgartMainz 05 2-2 VfB Stuttgart | German Bundesliga |
| 12 | Thu 12 Mar | 200-0 v Sigma OlomoucSigma Olomouc 0-0 Mainz 05 | UEFA Europa Conference League Round of 16 |
| 13 | Sun 15 Mar | 202-0 v Werder BremenWerder Bremen 0-2 Mainz 05 | German Bundesliga |
| 14 | Thu 19 Mar | 20 2-0 v Sigma OlomoucMainz 05 2-0 Sigma Olomouc | UEFA Europa Conference League Round of 16 |
| 15 | Sun 22 Mar | 20 2-1 v Eintracht FrankfurtMainz 05 2-1 Eintracht Frankfurt | German Bundesliga |
| 16 | Sat 4 Apr | 202-1 v TSG HoffenheimTSG Hoffenheim 1-2 Mainz 05 | German Bundesliga |
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