| 1 | Sat 24 Aug | 251-1 v 1 FC Union BerlinMainz 05 1-1 1 FC Union Berlin | German Bundesliga |
| 2 | Sat 31 Aug | 253-3 v VfB StuttgartVfB Stuttgart 3-3 Mainz 05 | German Bundesliga |
| 3 | Fri 20 Sep | 25 3-2 v FC AugsburgFC Augsburg 2-3 Mainz 05 | German Bundesliga |
| 4 | Sat 28 Sep | 25 0-2 v 1 FC HeidenheimMainz 05 0-2 1 FC Heidenheim | German Bundesliga |
| 5 | Sun 24 Nov | 253-0 v Holstein KielHolstein Kiel 0-3 Mainz 05 | German Bundesliga |
| 6 | Sun 8 Dec | 253-4 v VfL WolfsburgVfL Wolfsburg 4-3 Mainz 05 | German Bundesliga |
| 7 | Sat 11 Jan | 252-0 v VfL BochumMainz 05 2-0 VfL Bochum | German Bundesliga |
| 8 | Tue 14 Jan | 250-1 v Bayer 04 LeverkusenBayer 04 Leverkusen 1-0 Mainz 05 | German Bundesliga |
| 9 | Sun 19 Jan | 251-2 v 1 FC Union Berlin1 FC Union Berlin 2-1 Mainz 05 | German Bundesliga |
| 10 | Sat 25 Jan | 252-0 v VfB StuttgartMainz 05 2-0 VfB Stuttgart | German Bundesliga |
| 11 | Sun 16 Feb | 252-0 v 1 FC Heidenheim1 FC Heidenheim 0-2 Mainz 05 | German Bundesliga |
| 12 | Sat 22 Feb | 252-0 v FC St PauliMainz 05 2-0 FC St Pauli | German Bundesliga |
| 13 | Sat 1 Mar | 252-1 v RB LeipzigRB Leipzig 1-2 Mainz 05 | German Bundesliga |
| 14 | Fri 7 Mar | 253-1 v Borussia MönchengladbachBorussia Mönchengladbach 1-3 Mainz 05 | German Bundesliga |
| 15 | Sat 15 Mar | 252-2 v SC FreiburgMainz 05 2-2 SC Freiburg | German Bundesliga |
| 16 | Sun 30 Mar | 251-3 v Borussia DortmundBorussia Dortmund 3-1 Mainz 05 | German Bundesliga |
| 17 | Sat 5 Apr | 251-1 v Holstein KielMainz 05 1-1 Holstein Kiel | German Bundesliga |
| 18 | Sat 19 Apr | 252-2 v VfL WolfsburgMainz 05 2-2 VfL Wolfsburg | German Bundesliga |
| 19 | Sat 26 Apr | 250-3 v Bayern MunichBayern Munich 3-0 Mainz 05 | German Bundesliga |
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