| 1 | Wed 25 Jan 2023 | 171-2 v Borussia DortmundMainz 05 1-2 Borussia Dortmund | German Bundesliga |
| 2 | Sat 28 Jan 2023 | 175-2 v VfL BochumMainz 05 5-2 VfL Bochum | German Bundesliga |
| 3 | Sat 4 Feb 2023 | 17 1-2 v 1 FC Union Berlin1 FC Union Berlin 2-1 Mainz 05 | German Bundesliga |
| 4 | Sat 11 Feb 2023 | 173-1 v FC AugsburgMainz 05 3-1 FC Augsburg | German Bundesliga |
| 5 | Sun 19 Feb 2023 | 173-2 v Bayer 04 LeverkusenBayer 04 Leverkusen 2-3 Mainz 05 | German Bundesliga |
| 6 | Fri 24 Feb 2023 | 174-0 v Borussia MönchengladbachMainz 05 4-0 Borussia Mönchengladbach | German Bundesliga |
| 7 | Sat 4 Mar 2023 | 171-0 v 1899 HoffenheimMainz 05 1-0 1899 Hoffenheim | German Bundesliga |
| 8 | Sat 11 Mar 2023 | 171-1 v Hertha BerlinHertha Berlin 1-1 Mainz 05 | German Bundesliga |
| 9 | Sun 19 Mar 2023 | 17 1-1 v SC FreiburgMainz 05 1-1 SC Freiburg | German Bundesliga |
| 10 | Sat 1 Apr 2023 | 173-0 v RB LeipzigRB Leipzig 0-3 Mainz 05 | German Bundesliga |
| 11 | Sat 8 Apr 2023 | 172-2 v Werder BremenMainz 05 2-2 Werder Bremen | German Bundesliga |
| 12 | Sat 15 Apr 2023 | 17 1-1 v 1 FC Köln1 FC Köln 1-1 Mainz 05 | German Bundesliga |
| 13 | Sat 22 Apr 2023 | 173-1 v Bayern MunichMainz 05 3-1 Bayern Munich | German Bundesliga |
| 14 | Sun 30 Apr 2023 | 170-3 v VfL WolfsburgVfL Wolfsburg 3-0 Mainz 05 | German Bundesliga |
| 15 | Fri 5 May 2023 | 17 2-3 v FC Schalke 04Mainz 05 2-3 FC Schalke 04 | German Bundesliga |
| 16 | Sat 13 May 2023 | 170-3 v Eintracht FrankfurtEintracht Frankfurt 3-0 Mainz 05 | German Bundesliga |
| 17 | Sun 21 May 2023 | 17 1-4 v VfB StuttgartMainz 05 1-4 VfB Stuttgart | German Bundesliga |
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