| 1 | Sun 20 Sep 2020 | 9 1-3 v RB LeipzigRB Leipzig 3-1 Mainz 05 | German Bundesliga |
| 2 | Sat 26 Sep 2020 | 91-4 v VfB StuttgartMainz 05 1-4 VfB Stuttgart | German Bundesliga |
| 3 | Fri 2 Oct 2020 | 9 0-4 v 1. FC Union Berlin1. FC Union Berlin 4-0 Mainz 05 | German Bundesliga |
| 4 | Sat 17 Oct 2020 | 90-1 v Bayer 04 LeverkusenMainz 05 0-1 Bayer 04 Leverkusen | German Bundesliga |
| 5 | Sat 24 Oct 2020 | 92-3 v Borussia MönchengladbachMainz 05 2-3 Borussia Mönchengladbach | German Bundesliga |
| 6 | Sat 31 Oct 2020 | 91-3 v FC AugsburgFC Augsburg 3-1 Mainz 05 | German Bundesliga |
| 7 | Sat 7 Nov 2020 | 92-2 v FC Schalke 04Mainz 05 2-2 FC Schalke 04 | German Bundesliga |
| 8 | Sun 22 Nov 2020 | 93-1 v SC FreiburgSC Freiburg 1-3 Mainz 05 | German Bundesliga |
| 9 | Sun 29 Nov 2020 | 91-1 v 1899 HoffenheimMainz 05 1-1 1899 Hoffenheim | German Bundesliga |
| 10 | Sat 5 Dec 2020 | 91-2 v Arminia BielefeldArminia Bielefeld 2-1 Mainz 05 | German Bundesliga |
| 11 | Sat 12 Dec 2020 | 90-1 v 1. FC KölnMainz 05 0-1 1. FC Köln | German Bundesliga |
| 12 | Tue 15 Dec 2020 | 90-0 v Hertha BerlinHertha Berlin 0-0 Mainz 05 | German Bundesliga |
| 13 | Sat 19 Dec 2020 | 90-1 v Werder BremenMainz 05 0-1 Werder Bremen | German Bundesliga |
| 14 | Sun 3 Jan 2021 | 92-5 v Bayern MunichBayern Munich 5-2 Mainz 05 | German Bundesliga |
| 15 | Sat 9 Jan 2021 | 90-2 v Eintracht FrankfurtMainz 05 0-2 Eintracht Frankfurt | German Bundesliga |
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