| 1 | Sat 25 Aug 2012 | 323-2 v Lincoln CityLincoln City 2-3 Macclesfield Town | Blue Square Bet Premier |
| 2 | Mon 27 Aug 2012 | 322-0 v BarrowMacclesfield Town 2-0 Barrow | Blue Square Bet Premier |
| 3 | Sat 1 Sep 2012 | 321-4 v Luton TownLuton Town 4-1 Macclesfield Town | Blue Square Bet Premier |
| 4 | Tue 4 Sep 2012 | 324-3 v Stockport CountyStockport County 3-4 Macclesfield Town | Blue Square Bet Premier |
| 5 | Sat 8 Sep 2012 | 322-1 v Braintree TownMacclesfield Town 2-1 Braintree Town | Blue Square Bet Premier |
| 6 | Sat 15 Sep 2012 | 323-3 v Nuneaton TownNuneaton Town 3-3 Macclesfield Town | Blue Square Bet Premier |
| 7 | Sat 22 Sep 2012 | 321-2 v Forest Green RoversMacclesfield Town 1-2 Forest Green Rovers | Blue Square Bet Premier |
| 8 | Sat 29 Sep 2012 | 320-3 v Kidderminster HarriersKidderminster Harriers 3-0 Macclesfield Town | Blue Square Bet Premier |
| 9 | Sat 6 Oct 2012 | 321-2 v Alfreton TownMacclesfield Town 1-2 Alfreton Town | Blue Square Bet Premier |
| 10 | Tue 9 Oct 2012 | 322-2 v GatesheadGateshead 2-2 Macclesfield Town | Blue Square Bet Premier |
| 11 | Sat 13 Oct 2012 | 321-1 v Newport CountyMacclesfield Town 1-1 Newport County | Blue Square Bet Premier |
| 12 | Sat 10 Nov 2012 | 320-2 v Cambridge UnitedCambridge United 2-0 Macclesfield Town | Blue Square Bet Premier |
| 13 | Sat 17 Nov 2012 | 321-2 v Ebbsfleet UnitedMacclesfield Town 1-2 Ebbsfleet United | Blue Square Bet Premier |
| 14 | Tue 20 Nov 2012 | 320-3 v Mansfield TownMacclesfield Town 0-3 Mansfield Town | Blue Square Bet Premier |
| 15 | Tue 4 Dec 2012 | 323-2 v HydeMacclesfield Town 3-2 Hyde | Blue Square Bet Premier |
| 16 | Sat 8 Dec 2012 | 321-1 v Forest Green RoversForest Green Rovers 1-1 Macclesfield Town | Blue Square Bet Premier |
| 17 | Sat 15 Dec 2012 | 320-0 v Nuneaton TownMacclesfield Town 0-0 Nuneaton Town | Blue Square Bet Premier |
| 18 | Tue 18 Dec 2012 | 321-1 v BarrowBarrow 1-1 Macclesfield Town | FA Cup with Budweiser Second Round |
| 19 | Wed 26 Dec 2012 | 322-3 v SouthportSouthport 3-2 Macclesfield Town | Blue Square Bet Premier |
| 20 | Sat 29 Dec 2012 | 324-1 v BarrowMacclesfield Town 4-1 Barrow | FA Cup with Budweiser Second Round Replay |
| 21 | Tue 1 Jan 2013 | 322-2 v SouthportMacclesfield Town 2-2 Southport | Blue Square Bet Premier |
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