| 1 | Fri 10 Aug 2012 | 21-2 v Hereford UnitedHereford United 2-1 Macclesfield Town | Blue Square Bet Premier |
| 2 | Tue 14 Aug 2012 | 22-0 v WrexhamMacclesfield Town 2-0 Wrexham | Blue Square Bet Premier |
| 3 | Sat 18 Aug 2012 | 22-0 v DartfordMacclesfield Town 2-0 Dartford | Blue Square Bet Premier |
| 4 | Sat 25 Aug 2012 | 23-2 v Lincoln CityLincoln City 2-3 Macclesfield Town | Blue Square Bet Premier |
| 5 | Sat 8 Sep 2012 | 22-1 v Braintree TownMacclesfield Town 2-1 Braintree Town | Blue Square Bet Premier |
| 6 | Sat 15 Sep 2012 | 23-3 v Nuneaton TownNuneaton Town 3-3 Macclesfield Town | Blue Square Bet Premier |
| 7 | Sat 22 Sep 2012 | 21-2 v Forest Green RoversMacclesfield Town 1-2 Forest Green Rovers | Blue Square Bet Premier |
| 8 | Sat 29 Sep 2012 | 20-3 v Kidderminster HarriersKidderminster Harriers 3-0 Macclesfield Town | Blue Square Bet Premier |
| 9 | Sat 6 Oct 2012 | 21-2 v Alfreton TownMacclesfield Town 1-2 Alfreton Town | Blue Square Bet Premier |
| 10 | Tue 9 Oct 2012 | 22-2 v GatesheadGateshead 2-2 Macclesfield Town | Blue Square Bet Premier |
| 11 | Sat 13 Oct 2012 | 21-1 v Newport CountyMacclesfield Town 1-1 Newport County | Blue Square Bet Premier |
| 12 | Sat 27 Oct 2012 | 21-0 v Grimsby TownGrimsby Town 0-1 Macclesfield Town | Blue Square Bet Premier |
| 13 | Sat 3 Nov 2012 | 22-0 v Swindon TownSwindon Town 0-2 Macclesfield Town | FA Cup with Budweiser First Round |
| 14 | Tue 6 Nov 2012 | 22-0 v TamworthMacclesfield Town 2-0 Tamworth | Blue Square Bet Premier |
| 15 | Sat 10 Nov 2012 | 20-2 v Cambridge UnitedCambridge United 2-0 Macclesfield Town | Blue Square Bet Premier |
| 16 | Sat 17 Nov 2012 | 21-2 v Ebbsfleet UnitedMacclesfield Town 1-2 Ebbsfleet United | Blue Square Bet Premier |
| 17 | Tue 20 Nov 2012 | 20-3 v Mansfield TownMacclesfield Town 0-3 Mansfield Town | Blue Square Bet Premier |
| 18 | Tue 4 Dec 2012 | 23-2 v HydeMacclesfield Town 3-2 Hyde | Blue Square Bet Premier |
| 19 | Tue 18 Dec 2012 | 21-1 v BarrowBarrow 1-1 Macclesfield Town | FA Cup with Budweiser Second Round |
| 20 | Sat 29 Dec 2012 | 24-1 v BarrowMacclesfield Town 4-1 Barrow | FA Cup with Budweiser Second Round Replay |
| 21 | Tue 1 Jan 2013 | 22-2 v SouthportMacclesfield Town 2-2 Southport | Blue Square Bet Premier |
| 22 | Sat 26 Jan 2013 | 20-1 v Wigan AthleticMacclesfield Town 0-1 Wigan Athletic | FA Cup with Budweiser Fourth Round |
| 23 | Fri 1 Feb 2013 | 24-0 v Ebbsfleet UnitedEbbsfleet United 0-4 Macclesfield Town | Blue Square Bet Premier |
| 24 | Sat 9 Feb 2013 | 21-1 v HydeHyde 1-1 Macclesfield Town | Blue Square Bet Premier |
| 25 | Tue 12 Feb 2013 | 20-0 v TamworthTamworth 0-0 Macclesfield Town | Blue Square Bet Premier |
| 26 | Sat 16 Feb 2013 | 22-1 v Alfreton TownAlfreton Town 1-2 Macclesfield Town | Blue Square Bet Premier |
| 27 | Tue 19 Feb 2013 | 21-1 v Luton TownMacclesfield Town 1-1 Luton Town | Blue Square Bet Premier |
| 28 | Fri 22 Feb 2013 | 20-4 v GatesheadMacclesfield Town 0-4 Gateshead | Blue Square Bet Premier |
| 29 | Wed 6 Mar 2013 | 22-1 v Lincoln CityMacclesfield Town 2-1 Lincoln City | Blue Square Bet Premier |
| 30 | Sat 9 Mar 2013 | 22-0 v AFC Telford UnitedAFC Telford United 0-2 Macclesfield Town | Blue Square Bet Premier |
| 31 | Tue 12 Mar 2013 | 20-0 v WokingMacclesfield Town 0-0 Woking | Blue Square Bet Premier |
| 32 | Wed 27 Mar 2013 | 20-1 v BarrowBarrow 1-0 Macclesfield Town | Blue Square Bet Premier |
| 33 | Sat 30 Mar 2013 | 21-1 v Stockport CountyMacclesfield Town 1-1 Stockport County | Blue Square Bet Premier |
| 34 | Mon 1 Apr 2013 | 20-0 v WrexhamWrexham 0-0 Macclesfield Town | Blue Square Bet Premier |
| 35 | Wed 3 Apr 2013 | 21-3 v Grimsby TownMacclesfield Town 1-3 Grimsby Town | Blue Square Bet Premier |
| 36 | Sat 6 Apr 2013 | 20-1 v Hereford UnitedMacclesfield Town 0-1 Hereford United | Blue Square Bet Premier |
| 37 | Tue 9 Apr 2013 | 21-3 v Mansfield TownMansfield Town 3-1 Macclesfield Town | Blue Square Bet Premier |
| 38 | Thu 11 Apr 2013 | 21-4 v Newport CountyNewport County 4-1 Macclesfield Town | Blue Square Bet Premier |
| 39 | Sat 13 Apr 2013 | 24-5 v WokingWoking 5-4 Macclesfield Town | Blue Square Bet Premier |
| 40 | Sat 20 Apr 2013 | 22-1 v Cambridge UnitedMacclesfield Town 2-1 Cambridge United | Blue Square Bet Premier |
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