| 1 | Sun 29 Sep | 202-1 v ToulouseToulouse 1-2 Lyon | French Ligue 1 |
| 2 | Sun 20 Oct | 204-0 v Le HavreLe Havre 0-4 Lyon | French Ligue 1 |
| 3 | Sun 27 Oct | 202-2 v AuxerreLyon 2-2 Auxerre | French Ligue 1 |
| 4 | Thu 7 Nov | 202-2 v 1899 Hoffenheim1899 Hoffenheim 2-2 Lyon | UEFA Europa League Matchday 4 |
| 5 | Sat 18 Jan | 20 0-0 v ToulouseLyon 0-0 Toulouse | French Ligue 1 |
| 6 | Thu 23 Jan | 20 0-0 v FenerbahçeFenerbahçe 0-0 Lyon | UEFA Europa League Matchday 7 |
| 7 | Sun 26 Jan | 201-1 v NantesNantes 1-1 Lyon | French Ligue 1 |
| 8 | Thu 30 Jan | 201-1 v LudogoretsLyon 1-1 Ludogorets | UEFA Europa League Matchday 8 |
| 9 | Sun 2 Feb | 202-3 v MarseilleMarseille 3-2 Lyon | French Ligue 1 |
| 10 | Sun 9 Feb | 204-0 v ReimsLyon 4-0 Reims | French Ligue 1 |
| 11 | Sun 16 Feb | 204-1 v MontpellierMontpellier 1-4 Lyon | French Ligue 1 |
| 12 | Sun 23 Feb | 202-3 v Paris St GermainLyon 2-3 Paris St Germain | French Ligue 1 |
| 13 | Sun 2 Mar | 202-1 v BrestLyon 2-1 Brest | French Ligue 1 |
| 14 | Sun 9 Mar | 20 2-0 v NiceNice 0-2 Lyon | French Ligue 1 |
| 15 | Sun 13 Apr | 203-1 v AuxerreAuxerre 1-3 Lyon | French Ligue 1 |
| 16 | Sun 20 Apr | 201-2 v Saint ÉtienneSaint Étienne 2-1 Lyon | French Ligue 1 |
| 17 | Sat 26 Apr | 204-1 v RennesLyon 4-1 Rennes | French Ligue 1 |
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