| 1 | Sun 17 Aug | 273-3 v BrestBrest 3-3 Lille | French Ligue 1 |
| 2 | Sun 24 Aug | 271-0 v MonacoLille 1-0 Monaco | French Ligue 1 |
| 3 | Sat 30 Aug | 277-1 v LorientLorient 1-7 Lille | French Ligue 1 |
| 4 | Sun 14 Sep | 272-1 v ToulouseLille 2-1 Toulouse | French Ligue 1 |
| 5 | Sat 20 Sep | 270-3 v LensLens 3-0 Lille | French Ligue 1 |
| 6 | Thu 25 Sep | 272-1 v SK BrannLille 2-1 SK Brann | UEFA Europa League Matchday 1 |
| 7 | Sun 28 Sep | 270-1 v Olympique LyonnaisLille 0-1 Olympique Lyonnais | French Ligue 1 |
| 8 | Thu 2 Oct | 271-0 v RomaRoma 0-1 Lille | UEFA Europa League Matchday 2 |
| 9 | Sun 5 Oct | 271-1 v Paris St GermainLille 1-1 Paris St Germain | French Ligue 1 |
| 10 | Sun 19 Oct | 272-0 v NantesNantes 0-2 Lille | French Ligue 1 |
| 11 | Thu 23 Oct | 273-4 v PAOK FCLille 3-4 PAOK FC | UEFA Europa League Matchday 3 |
| 12 | Sun 26 Oct | 276-1 v MetzLille 6-1 Metz | French Ligue 1 |
| 13 | Wed 29 Oct | 270-2 v NiceNice 2-0 Lille | French Ligue 1 |
| 14 | Sun 2 Nov | 271-0 v AngersLille 1-0 Angers | French Ligue 1 |
| 15 | Thu 6 Nov | 270-1 v Crvena ZvezdaCrvena Zvezda 1-0 Lille | UEFA Europa League Matchday 4 |
| 16 | Sun 9 Nov | 270-2 v StrasbourgStrasbourg 2-0 Lille | French Ligue 1 |
| 17 | Sun 23 Nov | 274-2 v Paris FCLille 4-2 Paris FC | French Ligue 1 |
| 18 | Thu 27 Nov | 274-0 v Dinamo ZagrebLille 4-0 Dinamo Zagreb | UEFA Europa League Matchday 5 |
| 19 | Sun 30 Nov | 271-0 v Le HavreLe Havre 0-1 Lille | French Ligue 1 |
| 20 | Fri 5 Dec | 271-0 v Olympique MarseilleLille 1-0 Olympique Marseille | French Ligue 1 |
| 21 | Thu 11 Dec | 270-1 v Young BoysYoung Boys 1-0 Lille | UEFA Europa League Matchday 6 |
| 22 | Sun 14 Dec | 27 4-3 v AuxerreAuxerre 3-4 Lille | French Ligue 1 |
| 23 | Sat 3 Jan | 270-2 v RennesLille 0-2 Rennes | French Ligue 1 |
| 24 | Fri 16 Jan | 270-3 v Paris St GermainParis St Germain 3-0 Lille | French Ligue 1 |
| 25 | Thu 22 Jan | 271-2 v Celta VigoCelta Vigo 2-1 Lille | UEFA Europa League Matchday 7 |
| 26 | Sun 25 Jan | 271-4 v StrasbourgLille 1-4 Strasbourg | French Ligue 1 |
| 27 | Thu 29 Jan | 271-0 v SC FreiburgLille 1-0 SC Freiburg | UEFA Europa League Matchday 8 |
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