| 1 | Sat 30 Jul 2022 | 242-0 v Grimsby TownLeyton Orient 2-0 Grimsby Town | Sky Bet League Two |
| 2 | Tue 9 Aug 2022 | 24 0-2 v Forest Green RoversForest Green Rovers 2-0 Leyton Orient | Carabao Cup First Round |
| 3 | Tue 30 Aug 2022 | 240-5 v Oxford UnitedOxford United 5-0 Leyton Orient | Papa John’s Trophy |
| 4 | Tue 13 Sep 2022 | 241-0 v RochdaleRochdale 0-1 Leyton Orient | Sky Bet League Two |
| 5 | Sat 17 Sep 2022 | 241-0 v WalsallLeyton Orient 1-0 Walsall | Sky Bet League Two |
| 6 | Tue 20 Sep 2022 | 243-1 v Sutton UnitedLeyton Orient 3-1 Sutton United | Papa John’s Trophy |
| 7 | Sat 24 Sep 2022 | 242-0 v BarrowBarrow 0-2 Leyton Orient | Sky Bet League Two |
| 8 | Sat 12 Nov 2022 | 242-0 v Harrogate TownHarrogate Town 0-2 Leyton Orient | Sky Bet League Two |
| 9 | Sat 14 Jan 2023 | 240-0 v BarrowLeyton Orient 0-0 Barrow | Sky Bet League Two |
| 10 | Sat 4 Feb 2023 | 24 1-0 v AFC WimbledonLeyton Orient 1-0 AFC Wimbledon | Sky Bet League Two |
| 11 | Tue 7 Feb 2023 | 242-0 v Crewe AlexandraCrewe Alexandra 0-2 Leyton Orient | Sky Bet League Two |
| 12 | Sat 11 Feb 2023 | 24 1-1 v WalsallWalsall 1-1 Leyton Orient | Sky Bet League Two |
| 13 | Tue 14 Feb 2023 | 242-1 v RochdaleLeyton Orient 2-1 Rochdale | Sky Bet League Two |
| 14 | Sat 18 Feb 2023 | 241-0 v Crawley TownLeyton Orient 1-0 Crawley Town | Sky Bet League Two |
| 15 | Sat 25 Feb 2023 | 242-2 v Grimsby TownGrimsby Town 2-2 Leyton Orient | Sky Bet League Two |
| 16 | Sat 4 Mar 2023 | 241-1 v Swindon TownLeyton Orient 1-1 Swindon Town | Sky Bet League Two |
| 17 | Sat 18 Mar 2023 | 242-2 v Colchester UnitedLeyton Orient 2-2 Colchester United | Sky Bet League Two |
| 18 | Sat 25 Mar 2023 | 241-1 v Hartlepool UnitedHartlepool United 1-1 Leyton Orient | Sky Bet League Two |
| 19 | Sat 1 Apr 2023 | 241-0 v Carlisle UnitedLeyton Orient 1-0 Carlisle United | Sky Bet League Two |
| 20 | Fri 7 Apr 2023 | 24 2-0 v Salford CitySalford City 0-2 Leyton Orient | Sky Bet League Two |
| 21 | Mon 10 Apr 2023 | 242-2 v Harrogate TownLeyton Orient 2-2 Harrogate Town | Sky Bet League Two |
| 22 | Sat 22 Apr 2023 | 242-0 v Crewe AlexandraLeyton Orient 2-0 Crewe Alexandra | Sky Bet League Two |
| 23 | Tue 25 Apr 2023 | 242-1 v Mansfield TownMansfield Town 1-2 Leyton Orient | Sky Bet League Two |
| 24 | Mon 8 May 2023 | 241-1 v Bradford CityBradford City 1-1 Leyton Orient | Sky Bet League Two |
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