| 1 | Sat 10 Aug | 162-0 v Chatham TownLewes 2-0 Chatham Town | Isthmian League - Premier Division |
| 2 | Tue 13 Aug | 161-0 v Bognor Regis TownBognor Regis Town 0-1 Lewes | Isthmian League - Premier Division |
| 3 | Sat 17 Aug | 22-1 v Hashtag UnitedLewes 2-1 Hashtag United | Isthmian League - Premier Division |
| 4 | Sat 24 Aug | 2 3-1 v Cray WanderersCray Wanderers 1-3 Lewes | Isthmian League - Premier Division |
| 5 | Mon 26 Aug | 2 2-1 v WhitehawkLewes 2-1 Whitehawk | Isthmian League - Premier Division |
| 6 | Sat 31 Aug | 21-1 v Harefield UnitedHarefield United 1-1 Lewes | Emirates FA Cup First Qualifying Round |
| 7 | Tue 3 Sep | 20-0 v Harefield UnitedLewes 0-0 Harefield United | Emirates FA Cup First Qualifying Round Replay |
| 8 | Sat 7 Sep | 20-0 v Carshalton AthleticCarshalton Athletic 0-0 Lewes | Isthmian League - Premier Division |
| 9 | Tue 1 Oct | 23-1 v Three BridgesLewes 3-1 Three Bridges | Sussex County Cup Second Round |
| 10 | Sat 5 Oct | 2 6-3 v Bracknell TownLewes 6-3 Bracknell Town | Isuzu FA Trophy Third Qualifying Round |
| 11 | Sat 19 Oct | 20-2 v HorshamHorsham 2-0 Lewes | Isthmian League - Premier Division |
| 12 | Sat 26 Oct | 22-2 v Ashford UnitedLewes 2-2 Ashford United | Isuzu FA Trophy First Round |
| 13 | Sat 2 Nov | 21-1 v Chatham TownChatham Town 1-1 Lewes | Isthmian League - Premier Division |
| 14 | Sat 9 Nov | 2 0-0 v HendonHendon 0-0 Lewes | Isthmian League - Premier Division |
| 15 | Tue 12 Nov | 24-1 v Bognor Regis TownLewes 4-1 Bognor Regis Town | Isthmian League - Premier Division |
| 16 | Sat 16 Nov | 20-2 v AFC TottonLewes 0-2 AFC Totton | Isuzu FA Trophy Second Round |
| 17 | Sat 23 Nov | 20-2 v DartfordDartford 2-0 Lewes | Isthmian League - Premier Division |
| 18 | Tue 26 Nov | 21-3 v Dover AthleticLewes 1-3 Dover Athletic | Isthmian League - Premier Division |
| 19 | Sat 30 Nov | 22-1 v Canvey IslandLewes 2-1 Canvey Island | Isthmian League - Premier Division |
| 20 | Tue 10 Dec | 22-2 v Dulwich HamletLewes 2-2 Dulwich Hamlet | Isthmian League - Premier Division |
| 21 | Sat 14 Dec | 22-3 v Chichester CityLewes 2-3 Chichester City | Isthmian League - Premier Division |
| 22 | Sat 21 Dec | 22-2 v Wingate & FinchleyWingate & Finchley 2-2 Lewes | Isthmian League - Premier Division |
| 23 | Sat 28 Dec | 21-2 v Hashtag UnitedHashtag United 2-1 Lewes | Isthmian League - Premier Division |
| 24 | Sat 4 Jan | 22-2 v CheshuntLewes 2-2 Cheshunt | Isthmian League - Premier Division |
| 25 | Sat 18 Jan | 20-2 v HorshamLewes 0-2 Horsham | Isthmian League - Premier Division |
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