| 1 | Mon 19 Aug | 750-4 v AtalantaLecce 0-4 Atalanta |
| 2 | Sat 24 Aug | 750-2 v Inter MilanInter Milan 2-0 Lecce |
| 3 | Sat 31 Aug | 751-0 v CagliariLecce 1-0 Cagliari |
| 4 | Sun 15 Sep | 75 0-0 v TorinoTorino 0-0 Lecce |
| 5 | Sat 21 Sep | 752-2 v ParmaLecce 2-2 Parma |
| 6 | Fri 27 Sep | 750-3 v AC MilanAC Milan 3-0 Lecce |
| 7 | Sat 5 Oct | 750-1 v UdineseUdinese 1-0 Lecce |
| 8 | Sun 20 Oct | 750-6 v FiorentinaLecce 0-6 Fiorentina |
| 9 | Sat 26 Oct | 750-1 v NapoliNapoli 1-0 Lecce |
| 10 | Tue 29 Oct | 751-0 v Hellas VeronaLecce 1-0 Hellas Verona |
| 11 | Sat 2 Nov | 750-1 v BolognaBologna 1-0 Lecce |
| 12 | Sat 21 Dec | 751-2 v LazioLecce 1-2 Lazio |
| 13 | Mon 30 Dec | 750-2 v Como 1907Como 1907 2-0 Lecce |
| 14 | Sun 5 Jan | 750-0 v GenoaLecce 0-0 Genoa |
| 15 | Sat 11 Jan | 75 3-1 v EmpoliEmpoli 1-3 Lecce |
| 16 | Sun 19 Jan | 751-4 v CagliariCagliari 4-1 Lecce |
| 17 | Sun 26 Jan | 750-4 v Inter MilanLecce 0-4 Inter Milan |
| 18 | Fri 31 Jan | 753-1 v ParmaParma 1-3 Lecce |
| 19 | Sun 9 Feb | 750-0 v BolognaLecce 0-0 Bologna |
| 20 | Sun 16 Feb | 750-0 v MonzaMonza 0-0 Lecce |
| 21 | Fri 21 Feb | 750-1 v UdineseLecce 0-1 Udinese |
| 22 | Fri 28 Feb | 750-1 v FiorentinaFiorentina 1-0 Lecce |
| 23 | Sat 8 Mar | 752-3 v AC MilanLecce 2-3 AC Milan |
| 24 | Sun 6 Apr | 751-1 v VeneziaLecce 1-1 Venezia |
| 25 | Sat 12 Apr | 751-2 v JuventusJuventus 2-1 Lecce |
| 26 | Sat 19 Apr | 750-3 v Como 1907Lecce 0-3 Como 1907 |
| 27 | Sun 27 Apr | 751-1 v AtalantaAtalanta 1-1 Lecce |
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