| 1 | Sun 24 Oct 2021 | 32-1 v AntalyasporAntalyaspor 1-2 İstanbul Başakşehir | Turkish Süper Lig |
| 2 | Mon 1 Nov 2021 | 3 2-1 v Adana Demirsporİstanbul Başakşehir 2-1 Adana Demirspor | Turkish Süper Lig |
| 3 | Sat 6 Nov 2021 | 33-1 v Yeni MalatyasporYeni Malatyaspor 1-3 İstanbul Başakşehir | Turkish Süper Lig |
| 4 | Sat 20 Nov 2021 | 32-1 v Sivassporİstanbul Başakşehir 2-1 Sivasspor | Turkish Süper Lig |
| 5 | Fri 26 Nov 2021 | 30-0 v Altayİstanbul Başakşehir 0-0 Altay | Turkish Süper Lig |
| 6 | Sun 5 Dec 2021 | 33-0 v HataysporHatayspor 0-3 İstanbul Başakşehir | Turkish Süper Lig |
| 7 | Sat 11 Dec 2021 | 32-1 v Kasımpaşa SKİstanbul Başakşehir 2-1 Kasımpaşa SK | Turkish Süper Lig |
| 8 | Sat 18 Dec 2021 | 31-1 v GalatasarayGalatasaray 1-1 İstanbul Başakşehir | Turkish Süper Lig |
| 9 | Sat 25 Dec 2021 | 30-0 v TrabzonsporTrabzonspor 0-0 İstanbul Başakşehir | Turkish Süper Lig |
| 10 | Sat 8 Jan 2022 | 3 1-1 v AlanyasporAlanyaspor 1-1 İstanbul Başakşehir | Turkish Süper Lig |
| 11 | Wed 19 Jan 2022 | 30-1 v KayserisporKayserispor 1-0 İstanbul Başakşehir | Turkish Süper Lig |
| 12 | Sat 22 Jan 2022 | 31-2 v Göztepe SKİstanbul Başakşehir 1-2 Göztepe SK | Turkish Süper Lig |
| 13 | Sat 5 Feb 2022 | 31-0 v FenerbahçeFenerbahçe 0-1 İstanbul Başakşehir | Turkish Süper Lig |
| 14 | Sat 12 Feb 2022 | 32-0 v Gazişehir Gaziantepİstanbul Başakşehir 2-0 Gazişehir Gaziantep | Turkish Süper Lig |
| 15 | Fri 18 Feb 2022 | 32-0 v Çaykur RizesporÇaykur Rizespor 0-2 İstanbul Başakşehir | Turkish Süper Lig |
| 16 | Tue 22 Feb 2022 | 3 2-1 v Konyasporİstanbul Başakşehir 2-1 Konyaspor | Turkish Süper Lig |
| 17 | Sat 26 Feb 2022 | 31-2 v Fatih Karagümrükİstanbul Başakşehir 1-2 Fatih Karagümrük | Turkish Süper Lig |
| 18 | Mon 7 Mar 2022 | 32-2 v BeşiktaşBeşiktaş 2-2 İstanbul Başakşehir | Turkish Süper Lig |
| 19 | Mon 14 Mar 2022 | 30-1 v Antalyasporİstanbul Başakşehir 0-1 Antalyaspor | Turkish Süper Lig |
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