| 1 | Sat 7 Aug 2021 | 274-1 v Preston North EndPreston North End 1-4 Hull City | Sky Bet Championship |
| 2 | Sat 14 Aug 2021 | 270-3 v Queens Park RangersHull City 0-3 Queens Park Rangers | Sky Bet Championship |
| 3 | Wed 18 Aug 2021 | 270-1 v Derby CountyHull City 0-1 Derby County | Sky Bet Championship |
| 4 | Sat 21 Aug 2021 | 270-2 v FulhamFulham 2-0 Hull City | Sky Bet Championship |
| 5 | Sat 11 Sep 2021 | 270-0 v Swansea CitySwansea City 0-0 Hull City | Sky Bet Championship |
| 6 | Tue 14 Sep 2021 | 270-2 v Blackburn RoversBlackburn Rovers 2-0 Hull City | Sky Bet Championship |
| 7 | Sat 18 Sep 2021 | 271-3 v Sheffield UnitedHull City 1-3 Sheffield United | Sky Bet Championship |
| 8 | Wed 20 Oct 2021 | 271-2 v Peterborough UnitedHull City 1-2 Peterborough United | Sky Bet Championship |
| 9 | Sat 23 Oct 2021 | 270-1 v Luton TownLuton Town 1-0 Hull City | Sky Bet Championship |
| 10 | Sat 30 Oct 2021 | 270-1 v Coventry CityHull City 0-1 Coventry City | Sky Bet Championship |
| 11 | Wed 3 Nov 2021 | 270-1 v West Bromwich AlbionWest Bromwich Albion 1-0 Hull City | Sky Bet Championship |
| 12 | Sat 6 Nov 2021 | 272-0 v BarnsleyBarnsley 0-2 Hull City | Sky Bet Championship |
| 13 | Sat 20 Nov 2021 | 27 2-0 v Birmingham CityHull City 2-0 Birmingham City | Sky Bet Championship |
| 14 | Wed 24 Nov 2021 | 271-0 v Cardiff CityCardiff City 0-1 Hull City | Sky Bet Championship |
| 15 | Sat 27 Nov 2021 | 272-1 v MillwallHull City 2-1 Millwall | Sky Bet Championship |
| 16 | Sat 4 Dec 2021 | 271-1 v ReadingReading 1-1 Hull City | Sky Bet Championship |
| 17 | Sat 11 Dec 2021 | 272-2 v Bristol CityHull City 2-2 Bristol City | Sky Bet Championship |
| 18 | Sat 18 Dec 2021 | 271-2 v Nottingham ForestNottingham Forest 2-1 Hull City | Sky Bet Championship |
| 19 | Sat 1 Jan 2022 | 270-1 v BlackpoolBlackpool 1-0 Hull City | Sky Bet Championship |
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