| 1 | Fri 11 Feb 2022 | 291-0 v FC UtrechtHeracles Almelo 1-0 FC Utrecht | Dutch Eredivisie |
| 2 | Sat 19 Feb 2022 | 291-2 v AZ AlkmaarAZ Alkmaar 2-1 Heracles Almelo | Dutch Eredivisie |
| 3 | Sat 26 Feb 2022 | 292-0 v PEC ZwolleHeracles Almelo 2-0 PEC Zwolle | Dutch Eredivisie |
| 4 | Sun 6 Mar 2022 | 291-3 v PSV EindhovenPSV Eindhoven 3-1 Heracles Almelo | Dutch Eredivisie |
| 5 | Sun 13 Mar 2022 | 290-0 v VitesseHeracles Almelo 0-0 Vitesse | Dutch Eredivisie |
| 6 | Sun 3 Apr 2022 | 292-0 v Fortuna SittardFortuna Sittard 0-2 Heracles Almelo | Dutch Eredivisie |
| 7 | Sun 10 Apr 2022 | 291-4 v FeyenoordHeracles Almelo 1-4 Feyenoord | Dutch Eredivisie |
| 8 | Sun 24 Apr 2022 | 291-0 v FC GroningenFC Groningen 0-1 Heracles Almelo | Dutch Eredivisie |
| 9 | Sat 30 Apr 2022 | 291-1 v FC TwenteHeracles Almelo 1-1 FC Twente | Dutch Eredivisie |
| 10 | Sat 7 May 2022 | 290-2 v Willem IIWillem II 2-0 Heracles Almelo | Dutch Eredivisie |
| 11 | Wed 11 May 2022 | 290-2 v RKC WaalwijkRKC Waalwijk 2-0 Heracles Almelo | Dutch Eredivisie |
| 12 | Sun 15 May 2022 | 291-3 v Sparta RotterdamHeracles Almelo 1-3 Sparta Rotterdam | Dutch Eredivisie |
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