| 1 | Sun 13 Sep 2020 | 22-0 v ADO Den HaagHeracles Almelo 2-0 ADO Den Haag | Dutch Eredivisie |
| 2 | Sun 20 Sep 2020 | 20-4 v Willem IIWillem II 4-0 Heracles Almelo | Dutch Eredivisie |
| 3 | Sun 27 Sep 2020 | 21-1 v PSV EindhovenHeracles Almelo 1-1 PSV Eindhoven | Dutch Eredivisie |
| 4 | Sat 3 Oct 2020 | 20-3 v VitesseVitesse 3-0 Heracles Almelo | Dutch Eredivisie |
| 5 | Sat 17 Oct 2020 | 20-1 v RKC WaalwijkHeracles Almelo 0-1 RKC Waalwijk | Dutch Eredivisie |
| 6 | Sun 25 Oct 2020 | 21-1 v Sparta RotterdamSparta Rotterdam 1-1 Heracles Almelo | Dutch Eredivisie |
| 7 | Sun 1 Nov 2020 | 24-1 v FC UtrechtHeracles Almelo 4-1 FC Utrecht | Dutch Eredivisie |
| 8 | Sat 7 Nov 2020 | 22-3 v VVV VenloVVV Venlo 3-2 Heracles Almelo | Dutch Eredivisie |
| 9 | Sun 22 Nov 2020 | 20-5 v AjaxAjax 5-0 Heracles Almelo | Dutch Eredivisie |
| 10 | Sun 29 Nov 2020 | 21-2 v AZ AlkmaarHeracles Almelo 1-2 AZ Alkmaar | Dutch Eredivisie |
| 11 | Sun 6 Dec 2020 | 2 0-0 v FeyenoordFeyenoord 0-0 Heracles Almelo | Dutch Eredivisie |
| 12 | Fri 11 Dec 2020 | 21-2 v Fortuna SittardHeracles Almelo 1-2 Fortuna Sittard | Dutch Eredivisie |
| 13 | Sun 20 Dec 2020 | 22-1 v sc Heerenveensc Heerenveen 1-2 Heracles Almelo | Dutch Eredivisie |
| 14 | Wed 23 Dec 2020 | 21-0 v FC GroningenFC Groningen 0-1 Heracles Almelo | Dutch Eredivisie |
| 15 | Sat 9 Jan 2021 | 20-2 v VitesseHeracles Almelo 0-2 Vitesse | Dutch Eredivisie |
| 16 | Tue 12 Jan 2021 | 24-0 v FC EmmenHeracles Almelo 4-0 FC Emmen | Dutch Eredivisie |
| 17 | Sat 16 Jan 2021 | 2 0-2 v FC UtrechtFC Utrecht 2-0 Heracles Almelo | Dutch Eredivisie |
| 18 | Sat 23 Jan 2021 | 21-0 v sc HeerenveenHeracles Almelo 1-0 sc Heerenveen | Dutch Eredivisie |
| 19 | Tue 26 Jan 2021 | 22-2 v PEC ZwollePEC Zwolle 2-2 Heracles Almelo | Dutch Eredivisie |
| 20 | Sat 30 Jan 2021 | 21-0 v FC GroningenHeracles Almelo 1-0 FC Groningen | Dutch Eredivisie |
| 21 | Fri 5 Feb 2021 | 21-0 v Fortuna SittardFortuna Sittard 0-1 Heracles Almelo | Dutch Eredivisie |
| 22 | Sat 13 Feb 2021 | 20-2 v AjaxHeracles Almelo 0-2 Ajax | Dutch Eredivisie |
| 23 | Sun 21 Feb 2021 | 20-3 v RKC WaalwijkRKC Waalwijk 3-0 Heracles Almelo | Dutch Eredivisie |
| 24 | Sun 7 Mar 2021 | 22-1 v PEC ZwolleHeracles Almelo 2-1 PEC Zwolle | Dutch Eredivisie |
| 25 | Thu 13 May 2021 | 21-1 v FeyenoordHeracles Almelo 1-1 Feyenoord | Dutch Eredivisie |
| 26 | Sun 16 May 2021 | 20-5 v AZ AlkmaarAZ Alkmaar 5-0 Heracles Almelo | Dutch Eredivisie |
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