| 1 | Sat 14 Aug 2021 | 11-1 v Kasımpaşa SKHatayspor 1-1 Kasımpaşa SK | Turkish Süper Lig |
| 2 | Mon 23 Aug 2021 | 11-2 v GalatasarayGalatasaray 2-1 Hatayspor | Turkish Süper Lig |
| 3 | Sat 28 Aug 2021 | 15-0 v AlanyasporHatayspor 5-0 Alanyaspor | Turkish Süper Lig |
| 4 | Sun 12 Sep 2021 | 12-0 v Çaykur RizesporÇaykur Rizespor 0-2 Hatayspor | Turkish Süper Lig |
| 5 | Sun 19 Sep 2021 | 1 2-1 v KayserisporHatayspor 2-1 Kayserispor | Turkish Süper Lig |
| 6 | Wed 22 Sep 2021 | 12-0 v Göztepe SKGöztepe SK 0-2 Hatayspor | Turkish Süper Lig |
| 7 | Sun 26 Sep 2021 | 11-2 v FenerbahçeHatayspor 1-2 Fenerbahçe | Turkish Süper Lig |
| 8 | Sun 3 Oct 2021 | 1 2-0 v Yeni MalatyasporYeni Malatyaspor 0-2 Hatayspor | Turkish Süper Lig |
| 9 | Mon 18 Oct 2021 | 12-1 v Gazişehir GaziantepHatayspor 2-1 Gazişehir Gaziantep | Turkish Süper Lig |
| 10 | Sun 24 Oct 2021 | 11-1 v Fatih KaragümrükFatih Karagümrük 1-1 Hatayspor | Turkish Süper Lig |
| 11 | Sat 30 Oct 2021 | 11-0 v BeşiktaşHatayspor 1-0 Beşiktaş | Turkish Süper Lig |
| 12 | Sun 7 Nov 2021 | 10-1 v Adana DemirsporAdana Demirspor 1-0 Hatayspor | Turkish Süper Lig |
| 13 | Sat 20 Nov 2021 | 13-1 v AntalyasporHatayspor 3-1 Antalyaspor | Turkish Süper Lig |
| 14 | Sun 28 Nov 2021 | 10-4 v SivassporSivasspor 4-0 Hatayspor | Turkish Süper Lig |
| 15 | Sun 5 Dec 2021 | 10-3 v İstanbul BaşakşehirHatayspor 0-3 İstanbul Başakşehir | Turkish Süper Lig |
| 16 | Fri 10 Dec 2021 | 12-1 v AltayAltay 1-2 Hatayspor | Turkish Süper Lig |
| 17 | Sat 18 Dec 2021 | 10-2 v TrabzonsporTrabzonspor 2-0 Hatayspor | Turkish Süper Lig |
| 18 | Wed 22 Dec 2021 | 11-3 v KonyasporHatayspor 1-3 Konyaspor | Turkish Süper Lig |
| 19 | Sat 25 Dec 2021 | 11-0 v GiresunsporGiresunspor 0-1 Hatayspor | Turkish Süper Lig |
| 20 | Fri 4 Feb 2022 | 13-4 v KayserisporKayserispor 4-3 Hatayspor | Turkish Süper Lig |
| 21 | Mon 14 Feb 2022 | 12-1 v Göztepe SKHatayspor 2-1 Göztepe SK | Turkish Süper Lig |
| 22 | Sun 20 Feb 2022 | 10-2 v FenerbahçeFenerbahçe 2-0 Hatayspor | Turkish Süper Lig |
| 23 | Sun 27 Feb 2022 | 15-2 v Yeni MalatyasporHatayspor 5-2 Yeni Malatyaspor | Turkish Süper Lig |
| 24 | Mon 7 Mar 2022 | 12-2 v Gazişehir GaziantepGazişehir Gaziantep 2-2 Hatayspor | Turkish Süper Lig |
| 25 | Sat 12 Mar 2022 | 13-0 v Fatih KaragümrükHatayspor 3-0 Fatih Karagümrük | Turkish Süper Lig |
| 26 | Sat 19 Mar 2022 | 11-1 v BeşiktaşBeşiktaş 1-1 Hatayspor | Turkish Süper Lig |
| 27 | Mon 4 Apr 2022 | 10-0 v Adana DemirsporHatayspor 0-0 Adana Demirspor | Turkish Süper Lig |
| 28 | Mon 11 Apr 2022 | 11-4 v AntalyasporAntalyaspor 4-1 Hatayspor | Turkish Süper Lig |
| 29 | Sat 16 Apr 2022 | 1 1-1 v SivassporHatayspor 1-1 Sivasspor | Turkish Süper Lig |
| 30 | Sun 24 Apr 2022 | 10-3 v İstanbul Başakşehirİstanbul Başakşehir 3-0 Hatayspor | Turkish Süper Lig |
| 31 | Sat 30 Apr 2022 | 10-1 v AltayHatayspor 0-1 Altay | Turkish Süper Lig |
| 32 | Fri 6 May 2022 | 11-1 v TrabzonsporHatayspor 1-1 Trabzonspor | Turkish Süper Lig |
| 33 | Sun 15 May 2022 | 11-3 v KonyasporKonyaspor 3-1 Hatayspor | Turkish Süper Lig |
| 34 | Sun 22 May 2022 | 14-1 v GiresunsporHatayspor 4-1 Giresunspor | Turkish Süper Lig |
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