| 1 | Sat 13 Oct 2012 | 0-2 v Solihull MoorsSolihull Moors 2-0 Guiseley | Blue Square Bet North |
| 2 | Tue 30 Oct 2012 | 3-1 v AltrinchamAltrincham 1-3 Guiseley | Blue Square Bet North |
| 3 | Sat 3 Nov 2012 | 92-2 v BarrowGuiseley 2-2 Barrow | FA Cup with Budweiser First Round |
| 4 | Tue 13 Nov 2012 | 90-1 v BarrowBarrow 1-0 Guiseley | FA Cup with Budweiser First Round Replay |
| 5 | Sat 17 Nov 2012 | 93-1 v Boston UnitedBoston United 1-3 Guiseley | Blue Square Bet North |
| 6 | Tue 20 Nov 2012 | 93-3 v Worcester CityGuiseley 3-3 Worcester City | Blue Square Bet North |
| 7 | Sat 1 Dec 2012 | 93-0 v Hinckley UnitedHinckley United 0-3 Guiseley | Blue Square Bet North |
| 8 | Sat 8 Dec 2012 | 92-1 v HistonGuiseley 2-1 Histon | Blue Square Bet North |
| 9 | Wed 26 Dec 2012 | 91-0 v Bradford Park AvenueGuiseley 1-0 Bradford Park Avenue | Blue Square Bet North |
| 10 | Tue 1 Jan 2013 | 93-1 v Bradford Park AvenueBradford Park Avenue 1-3 Guiseley | Blue Square Bet North |
| 11 | Sat 5 Jan 2013 | 95-2 v Bishop's StortfordBishop's Stortford 2-5 Guiseley | Blue Square Bet North |
| 12 | Tue 8 Jan 2013 | 92-1 v Corby TownGuiseley 2-1 Corby Town | Blue Square Bet North |
| 13 | Sat 12 Jan 2013 | 91-0 v Oxford CityGuiseley 1-0 Oxford City | Blue Square Bet North |
| 14 | Sat 9 Feb 2013 | 92-1 v Boston UnitedGuiseley 2-1 Boston United | Blue Square Bet North |
| 15 | Tue 12 Feb 2013 | 92-2 v Gloucester CityGloucester City 2-2 Guiseley | Blue Square Bet North |
| 16 | Sat 30 Mar 2013 | 92-1 v Gainsborough TrinityGainsborough Trinity 1-2 Guiseley | Blue Square Bet North |
| 17 | Mon 1 Apr 2013 | 92-0 v WorkingtonGuiseley 2-0 Workington | Blue Square Bet North |
| 18 | Sat 6 Apr 2013 | 90-1 v Brackley TownBrackley Town 1-0 Guiseley | Blue Square Bet North |
| 19 | Tue 9 Apr 2013 | 91-1 v Stalybridge CelticStalybridge Celtic 1-1 Guiseley | Blue Square Bet North |
| 20 | Thu 11 Apr 2013 | 91-1 v AltrinchamGuiseley 1-1 Altrincham | Blue Square Bet North |
| 21 | Sat 13 Apr 2013 | 92-1 v ChesterGuiseley 2-1 Chester | Blue Square Bet North |
| 22 | Tue 23 Apr 2013 | 92-1 v Harrogate TownHarrogate Town 1-2 Guiseley | Blue Square Bet North |
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