| 1 | Sat 18 Aug 2012 | 4-1 v HistonHiston 1-4 Guiseley | Blue Square Bet North |
| 2 | Tue 21 Aug 2012 | 7-1 v DroylsdenGuiseley 7-1 Droylsden | Blue Square Bet North |
| 3 | Tue 4 Sep 2012 | 2-0 v Colwyn BayColwyn Bay 0-2 Guiseley | Blue Square Bet North |
| 4 | Sat 8 Sep 2012 | 0-4 v ChesterChester 4-0 Guiseley | Blue Square Bet North |
| 5 | Sat 15 Sep 2012 | 1-2 v Bishop's StortfordGuiseley 1-2 Bishop's Stortford | Blue Square Bet North |
| 6 | Tue 18 Sep 2012 | 2-0 v Harrogate TownGuiseley 2-0 Harrogate Town | Blue Square Bet North |
| 7 | Sat 29 Sep 2012 | 3-0 v Oxford CityOxford City 0-3 Guiseley | Blue Square Bet North |
| 8 | Tue 2 Oct 2012 | 1-0 v Stalybridge CelticGuiseley 1-0 Stalybridge Celtic | Blue Square Bet North |
| 9 | Sat 13 Oct 2012 | 0-2 v Solihull MoorsSolihull Moors 2-0 Guiseley | Blue Square Bet North |
| 10 | Sat 27 Oct 2012 | 2-1 v Vauxhall MotorsGuiseley 2-1 Vauxhall Motors | Blue Square Bet North |
| 11 | Tue 30 Oct 2012 | 3-1 v AltrinchamAltrincham 1-3 Guiseley | Blue Square Bet North |
| 12 | Sat 3 Nov 2012 | 82-2 v BarrowGuiseley 2-2 Barrow | FA Cup with Budweiser First Round |
| 13 | Tue 13 Nov 2012 | 80-1 v BarrowBarrow 1-0 Guiseley | FA Cup with Budweiser First Round Replay |
| 14 | Sat 17 Nov 2012 | 83-1 v Boston UnitedBoston United 1-3 Guiseley | Blue Square Bet North |
| 15 | Tue 20 Nov 2012 | 83-3 v Worcester CityGuiseley 3-3 Worcester City | Blue Square Bet North |
| 16 | Sat 1 Dec 2012 | 83-0 v Hinckley UnitedHinckley United 0-3 Guiseley | Blue Square Bet North |
| 17 | Wed 26 Dec 2012 | 81-0 v Bradford Park AvenueGuiseley 1-0 Bradford Park Avenue | Blue Square Bet North |
| 18 | Tue 1 Jan 2013 | 83-1 v Bradford Park AvenueBradford Park Avenue 1-3 Guiseley | Blue Square Bet North |
| 19 | Sat 5 Jan 2013 | 85-2 v Bishop's StortfordBishop's Stortford 2-5 Guiseley | Blue Square Bet North |
| 20 | Tue 8 Jan 2013 | 82-1 v Corby TownGuiseley 2-1 Corby Town | Blue Square Bet North |
| 21 | Sat 12 Jan 2013 | 81-0 v Oxford CityGuiseley 1-0 Oxford City | Blue Square Bet North |
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