| 1 | Sat 2 Aug | 73-0 v Crawley TownGrimsby Town 3-0 Crawley Town | Sky Bet League Two |
| 2 | Sat 9 Aug | 73-3 v Harrogate TownHarrogate Town 3-3 Grimsby Town | Sky Bet League Two |
| 3 | Tue 12 Aug | 73-1 v Shrewsbury TownGrimsby Town 3-1 Shrewsbury Town | Carabao Cup First Round |
| 4 | Sat 16 Aug | 72-1 v Newport CountyGrimsby Town 2-1 Newport County | Sky Bet League Two |
| 5 | Tue 19 Aug | 71-0 v WalsallWalsall 0-1 Grimsby Town | Sky Bet League Two |
| 6 | Sat 13 Sep | 71-1 v Cambridge UnitedGrimsby Town 1-1 Cambridge United | Sky Bet League Two |
| 7 | Tue 16 Sep | 71-0 v Sheffield WednesdaySheffield Wednesday 0-1 Grimsby Town | Carabao Cup Third Round |
| 8 | Sat 20 Sep | 70-3 v BarnetBarnet 3-0 Grimsby Town | Sky Bet League Two |
| 9 | Sat 27 Sep | 77-1 v Cheltenham TownGrimsby Town 7-1 Cheltenham Town | Sky Bet League Two |
| 10 | Sat 4 Oct | 72-0 v Salford CitySalford City 0-2 Grimsby Town | Sky Bet League Two |
| 11 | Tue 7 Oct | 70-3 v Doncaster RoversGrimsby Town 0-3 Doncaster Rovers | EFL Trophy Northern Group C |
| 12 | Sat 11 Oct | 71-2 v Colchester UnitedGrimsby Town 1-2 Colchester United | Sky Bet League Two |
| 13 | Sat 18 Oct | 71-0 v GillinghamGrimsby Town 1-0 Gillingham | Sky Bet League Two |
| 14 | Sat 25 Oct | 72-3 v Crewe AlexandraCrewe Alexandra 3-2 Grimsby Town | Sky Bet League Two |
| 15 | Sat 1 Nov | 73-1 v Ebbsfleet UnitedGrimsby Town 3-1 Ebbsfleet United | Emirates FA Cup First Round |
| 16 | Tue 4 Nov | 75-3 v Everton U21Grimsby Town 5-3 Everton U21 | EFL Trophy Northern Group C |
| 17 | Sat 8 Nov | 72-2 v BarrowBarrow 2-2 Grimsby Town | Sky Bet League Two |
| 18 | Sat 15 Nov | 70-1 v ChesterfieldGrimsby Town 0-1 Chesterfield | Sky Bet League Two |
| 19 | Sat 22 Nov | 72-2 v Swindon TownSwindon Town 2-2 Grimsby Town | Sky Bet League Two |
| 20 | Thu 27 Nov | 71-2 v Tranmere RoversGrimsby Town 1-2 Tranmere Rovers | Sky Bet League Two |
| 21 | Tue 9 Dec | 71-1 v Shrewsbury TownShrewsbury Town 1-1 Grimsby Town | Sky Bet League Two |
| 22 | Sat 13 Dec | 70-2 v Notts CountyGrimsby Town 0-2 Notts County | Sky Bet League Two |
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