| 1 | Sat 20 Dec | 423-1 v RB LeipzigRB Leipzig 1-3 Bayer Leverkusen |
| 2 | Wed 4 Mar | 421-0 v Hamburger SVHamburger SV 0-1 Bayer Leverkusen |
| 3 | Sat 7 Mar | 423-3 v SC FreiburgSC Freiburg 3-3 Bayer Leverkusen |
| 4 | Sat 14 Mar | 421-1 v Bayern MunichBayer Leverkusen 1-1 Bayern Munich |
| 5 | Sat 21 Mar | 423-3 v 1 FC Heidenheim1 FC Heidenheim 3-3 Bayer Leverkusen |
| 6 | Sat 4 Apr | 426-3 v VfL WolfsburgBayer Leverkusen 6-3 VfL Wolfsburg |
| 7 | Sat 11 Apr | 421-0 v Borussia DortmundBorussia Dortmund 0-1 Bayer Leverkusen |
| 8 | Sat 18 Apr | 421-2 v FC AugsburgBayer Leverkusen 1-2 FC Augsburg |
| 9 | Sat 25 Apr | 422-1 v 1 FC Köln1 FC Köln 1-2 Bayer Leverkusen |
| 10 | Sat 2 May | 424-1 v RB LeipzigBayer Leverkusen 4-1 RB Leipzig |
| 11 | Sat 9 May | 421-3 v VfB StuttgartVfB Stuttgart 3-1 Bayer Leverkusen |
| 12 | Sat 16 May | 421-1 v Hamburger SVBayer Leverkusen 1-1 Hamburger SV |
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