| 1 | Wed 21 Jul 2021 | 11-5 v PSV EindhovenPSV Eindhoven 5-1 Galatasaray | UEFA Champions League Second Qualifying Round |
| 2 | Wed 28 Jul 2021 | 11-2 v PSV EindhovenGalatasaray 1-2 PSV Eindhoven | UEFA Champions League Second Qualifying Round |
| 3 | Thu 5 Aug 2021 | 1 1-1 v St JohnstoneGalatasaray 1-1 St Johnstone | UEFA Europa League First Qualifying Round |
| 4 | Thu 12 Aug 2021 | 14-2 v St JohnstoneSt Johnstone 2-4 Galatasaray | UEFA Europa League First Qualifying Round |
| 5 | Mon 16 Aug 2021 | 12-0 v GiresunsporGiresunspor 0-2 Galatasaray | Turkish Süper Lig |
| 6 | Thu 19 Aug 2021 | 11-1 v Randers FCRanders FC 1-1 Galatasaray | UEFA Europa League Qualifying Play-off Round |
| 7 | Mon 23 Aug 2021 | 12-1 v HataysporGalatasaray 2-1 Hatayspor | Turkish Süper Lig |
| 8 | Thu 26 Aug 2021 | 1 2-1 v Randers FCGalatasaray 2-1 Randers FC | UEFA Europa League Qualifying Play-off Round |
| 9 | Sun 29 Aug 2021 | 12-2 v Kasımpaşa SKKasımpaşa SK 2-2 Galatasaray | Turkish Süper Lig |
| 10 | Sun 12 Sep 2021 | 12-2 v TrabzonsporTrabzonspor 2-2 Galatasaray | Turkish Süper Lig |
| 11 | Thu 16 Sep 2021 | 1 1-0 v LazioGalatasaray 1-0 Lazio | UEFA Europa League Group E |
| 12 | Sun 19 Sep 2021 | 10-1 v AlanyasporGalatasaray 0-1 Alanyaspor | Turkish Süper Lig |
| 13 | Wed 22 Sep 2021 | 10-3 v KayserisporKayserispor 3-0 Galatasaray | Turkish Süper Lig |
| 14 | Sun 26 Sep 2021 | 12-1 v Göztepe SKGalatasaray 2-1 Göztepe SK | Turkish Süper Lig |
| 15 | Thu 30 Sep 2021 | 10-0 v MarseilleMarseille 0-0 Galatasaray | UEFA Europa League Group E |
| 16 | Sun 3 Oct 2021 | 1 3-2 v Çaykur RizesporÇaykur Rizespor 2-3 Galatasaray | Turkish Süper Lig |
| 17 | Sun 17 Oct 2021 | 11-0 v KonyasporGalatasaray 1-0 Konyaspor | Turkish Süper Lig |
| 18 | Thu 21 Oct 2021 | 11-0 v Lokomotiv MoscowLokomotiv Moscow 0-1 Galatasaray | UEFA Europa League Group E |
| 19 | Mon 25 Oct 2021 | 11-2 v BeşiktaşBeşiktaş 2-1 Galatasaray | Turkish Süper Lig |
| 20 | Sun 31 Oct 2021 | 12-0 v Gazişehir GaziantepGalatasaray 2-0 Gazişehir Gaziantep | Turkish Süper Lig |
| 21 | Thu 4 Nov 2021 | 11-1 v Lokomotiv MoscowGalatasaray 1-1 Lokomotiv Moscow | UEFA Europa League Group E |
| 22 | Sun 7 Nov 2021 | 11-1 v Fatih KaragümrükFatih Karagümrük 1-1 Galatasaray | Turkish Süper Lig |
| 23 | Sun 21 Nov 2021 | 1 1-2 v FenerbahçeGalatasaray 1-2 Fenerbahçe | Turkish Süper Lig |
| 24 | Thu 25 Nov 2021 | 14-2 v MarseilleGalatasaray 4-2 Marseille | UEFA Europa League Group E |
| 25 | Sun 28 Nov 2021 | 10-0 v Yeni MalatyasporYeni Malatyaspor 0-0 Galatasaray | Turkish Süper Lig |
| 26 | Sat 4 Dec 2021 | 1 2-2 v AltayGalatasaray 2-2 Altay | Turkish Süper Lig |
| 27 | Thu 9 Dec 2021 | 10-0 v LazioLazio 0-0 Galatasaray | UEFA Europa League Group E |
| 28 | Mon 13 Dec 2021 | 10-1 v SivassporSivasspor 1-0 Galatasaray | Turkish Süper Lig |
| 29 | Sun 20 Mar 2022 | 11-3 v Gazişehir GaziantepGazişehir Gaziantep 3-1 Galatasaray | Turkish Süper Lig |
| 30 | Sat 2 Apr 2022 | 12-0 v Fatih KaragümrükGalatasaray 2-0 Fatih Karagümrük | Turkish Süper Lig |
| 31 | Sun 10 Apr 2022 | 10-2 v FenerbahçeFenerbahçe 2-0 Galatasaray | Turkish Süper Lig |
| 32 | Mon 18 Apr 2022 | 12-0 v Yeni MalatyasporGalatasaray 2-0 Yeni Malatyaspor | Turkish Süper Lig |
| 33 | Sun 24 Apr 2022 | 11-0 v AltayAltay 0-1 Galatasaray | Turkish Süper Lig |
| 34 | Sun 1 May 2022 | 12-3 v SivassporGalatasaray 2-3 Sivasspor | Turkish Süper Lig |
| 35 | Sat 7 May 2022 | 10-0 v İstanbul Başakşehirİstanbul Başakşehir 0-0 Galatasaray | Turkish Süper Lig |
| 36 | Mon 16 May 2022 | 13-2 v Adana DemirsporGalatasaray 3-2 Adana Demirspor | Turkish Süper Lig |
| 37 | Fri 20 May 2022 | 11-1 v AntalyasporAntalyaspor 1-1 Galatasaray | Turkish Süper Lig |
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