| 1 | Sat 14 Aug 2021 | 42-1 v FC TwenteFortuna Sittard 2-1 FC Twente | Dutch Eredivisie |
| 2 | Fri 27 Aug 2021 | 42-2 v RKC WaalwijkFortuna Sittard 2-2 RKC Waalwijk | Dutch Eredivisie |
| 3 | Sun 12 Sep 2021 | 41-3 v Sparta RotterdamSparta Rotterdam 3-1 Fortuna Sittard | Dutch Eredivisie |
| 4 | Sat 18 Sep 2021 | 40-1 v sc Heerenveensc Heerenveen 1-0 Fortuna Sittard | Dutch Eredivisie |
| 5 | Tue 21 Sep 2021 | 4 0-5 v AjaxFortuna Sittard 0-5 Ajax | Dutch Eredivisie |
| 6 | Sat 25 Sep 2021 | 4 1-1 v VitesseVitesse 1-1 Fortuna Sittard | Dutch Eredivisie |
| 7 | Sat 2 Oct 2021 | 41-3 v NEC NijmegenFortuna Sittard 1-3 NEC Nijmegen | Dutch Eredivisie |
| 8 | Sat 20 Nov 2021 | 41-3 v Heracles AlmeloHeracles Almelo 3-1 Fortuna Sittard | Dutch Eredivisie |
| 9 | Sat 27 Nov 2021 | 4 1-4 v FC GroningenFortuna Sittard 1-4 FC Groningen | Dutch Eredivisie |
| 10 | Sat 11 Dec 2021 | 41-0 v PEC ZwollePEC Zwolle 0-1 Fortuna Sittard | Dutch Eredivisie |
| 11 | Sat 18 Dec 2021 | 42-2 v FC UtrechtFortuna Sittard 2-2 FC Utrecht | Dutch Eredivisie |
| 12 | Wed 22 Dec 2021 | 40-5 v AjaxAjax 5-0 Fortuna Sittard | Dutch Eredivisie |
| 13 | Sun 16 Jan 2022 | 41-2 v AZ AlkmaarFortuna Sittard 1-2 AZ Alkmaar | Dutch Eredivisie |
| 14 | Sun 23 Jan 2022 | 4 1-2 v RKC WaalwijkRKC Waalwijk 2-1 Fortuna Sittard | Dutch Eredivisie |
| 15 | Sat 12 Feb 2022 | 4 1-0 v FC GroningenFC Groningen 0-1 Fortuna Sittard | Dutch Eredivisie |
| 16 | Sun 24 Apr 2022 | 41-0 v Go Ahead EaglesFortuna Sittard 1-0 Go Ahead Eagles | Dutch Eredivisie |
| 17 | Sun 1 May 2022 | 41-3 v FeyenoordFortuna Sittard 1-3 Feyenoord | Dutch Eredivisie |
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