| 1 | Sun 14 Aug 2022 | 83-2 v CremoneseFiorentina 3-2 Cremonese | Italian Serie A |
| 2 | Sun 21 Aug 2022 | 80-0 v EmpoliEmpoli 0-0 Fiorentina | Italian Serie A |
| 3 | Sun 28 Aug 2022 | 80-0 v NapoliFiorentina 0-0 Napoli | Italian Serie A |
| 4 | Wed 31 Aug 2022 | 80-1 v UdineseUdinese 1-0 Fiorentina | Italian Serie A |
| 5 | Thu 8 Sep 2022 | 81-1 v Rīgas FSFiorentina 1-1 Rīgas FS | UEFA Europa Conference League Group A |
| 6 | Sun 11 Sep 2022 | 81-2 v BolognaBologna 2-1 Fiorentina | Italian Serie A |
| 7 | Thu 15 Sep 2022 | 80-3 v İstanbul Başakşehirİstanbul Başakşehir 3-0 Fiorentina | UEFA Europa Conference League Group A |
| 8 | Sun 18 Sep 2022 | 82-0 v Hellas VeronaFiorentina 2-0 Hellas Verona | Italian Serie A |
| 9 | Sun 2 Oct 2022 | 80-1 v AtalantaAtalanta 1-0 Fiorentina | Italian Serie A |
| 10 | Thu 6 Oct 2022 | 83-0 v Heart of MidlothianHeart of Midlothian 0-3 Fiorentina | UEFA Europa Conference League Group A |
| 11 | Mon 10 Oct 2022 | 80-4 v LazioFiorentina 0-4 Lazio | Italian Serie A |
| 12 | Thu 13 Oct 2022 | 85-1 v Heart of MidlothianFiorentina 5-1 Heart of Midlothian | UEFA Europa Conference League Group A |
| 13 | Thu 27 Oct 2022 | 82-1 v İstanbul BaşakşehirFiorentina 2-1 İstanbul Başakşehir | UEFA Europa Conference League Group A |
| 14 | Sun 30 Oct 2022 | 82-1 v SpeziaSpezia 1-2 Fiorentina | Italian Serie A |
| 15 | Thu 3 Nov 2022 | 83-0 v Rīgas FSRīgas FS 0-3 Fiorentina | UEFA Europa Conference League Group A |
| 16 | Sun 6 Nov 2022 | 82-0 v SampdoriaSampdoria 0-2 Fiorentina | Italian Serie A |
| 17 | Wed 9 Nov 2022 | 82-1 v SalernitanaFiorentina 2-1 Salernitana | Italian Serie A |
| 18 | Sun 13 Nov 2022 | 8 1-2 v AC MilanAC Milan 2-1 Fiorentina | Italian Serie A |
| 19 | Wed 4 Jan 2023 | 81-1 v MonzaFiorentina 1-1 Monza | Italian Serie A |
| 20 | Sat 7 Jan 2023 | 82-1 v SassuoloFiorentina 2-1 Sassuolo | Italian Serie A |
| 21 | Sat 21 Jan 2023 | 8 0-1 v TorinoFiorentina 0-1 Torino | Italian Serie A |
| 22 | Sun 29 Jan 2023 | 8 1-1 v LazioLazio 1-1 Fiorentina | Italian Serie A |
| 23 | Sun 5 Feb 2023 | 81-2 v BolognaFiorentina 1-2 Bologna | Italian Serie A |
| 24 | Sun 12 Feb 2023 | 80-1 v JuventusJuventus 1-0 Fiorentina | Italian Serie A |
| 25 | Thu 16 Feb 2023 | 84-0 v Sporting BragaSporting Braga 0-4 Fiorentina | UEFA Europa Conference League |
| 26 | Sun 19 Feb 2023 | 81-1 v EmpoliFiorentina 1-1 Empoli | Italian Serie A |
| 27 | Thu 23 Feb 2023 | 83-2 v Sporting BragaFiorentina 3-2 Sporting Braga | UEFA Europa Conference League |
| 28 | Mon 27 Feb 2023 | 83-0 v Hellas VeronaHellas Verona 0-3 Fiorentina | Italian Serie A |
| 29 | Sun 12 Mar 2023 | 82-0 v CremoneseCremonese 0-2 Fiorentina | Italian Serie A |
| 30 | Thu 16 Mar 2023 | 84-1 v SivassporSivasspor 1-4 Fiorentina | UEFA Europa Conference League Round of 16 |
| 31 | Sun 19 Mar 2023 | 81-0 v LecceFiorentina 1-0 Lecce | Italian Serie A |
| 32 | Sat 1 Apr 2023 | 81-0 v Inter MilanInter Milan 0-1 Fiorentina | Italian Serie A |
| 33 | Sun 23 Apr 2023 | 82-3 v MonzaMonza 3-2 Fiorentina | Italian Serie A |
| 34 | Sun 30 Apr 2023 | 85-0 v SampdoriaFiorentina 5-0 Sampdoria | Italian Serie A |
| 35 | Sun 7 May 2023 | 80-1 v NapoliNapoli 1-0 Fiorentina | Italian Serie A |
| 36 | Sun 21 May 2023 | 81-1 v TorinoTorino 1-1 Fiorentina | Italian Serie A |
| 37 | Sat 27 May 2023 | 8 2-1 v RomaFiorentina 2-1 Roma | Italian Serie A |
| 38 | Fri 2 Jun 2023 | 83-1 v SassuoloSassuolo 1-3 Fiorentina | Italian Serie A |
| 39 | Wed 7 Jun 2023 | 81-2 v West Ham UnitedFiorentina 1-2 West Ham United | UEFA Europa Conference League Final |
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