| 1 | Sat 7 Feb | 65-0 v sc HeerenveenFC Twente 5-0 sc Heerenveen | Dutch Eredivisie |
| 2 | Sun 15 Feb | 61-1 v TelstarTelstar 1-1 FC Twente | Dutch Eredivisie |
| 3 | Sun 22 Feb | 62-1 v FC GroningenFC Twente 2-1 FC Groningen | Dutch Eredivisie |
| 4 | Sun 1 Mar | 62-0 v FeyenoordFC Twente 2-0 Feyenoord | Dutch Eredivisie |
| 5 | Sun 8 Mar | 64-1 v Go Ahead EaglesGo Ahead Eagles 1-4 FC Twente | Dutch Eredivisie |
| 6 | Sun 15 Mar | 60-2 v FC UtrechtFC Twente 0-2 FC Utrecht | Dutch Eredivisie |
| 7 | Sat 21 Mar | 62-1 v Fortuna SittardFortuna Sittard 1-2 FC Twente | Dutch Eredivisie |
| 8 | Sat 4 Apr | 62-1 v AjaxAjax 1-2 FC Twente | Dutch Eredivisie |
| 9 | Fri 10 Apr | 62-1 v VolendamFC Twente 2-1 Volendam | Dutch Eredivisie |
| 10 | Sat 25 Apr | 61-1 v NEC NijmegenFC Twente 1-1 NEC Nijmegen | Dutch Eredivisie |
| 11 | Sun 3 May | 62-2 v AZ AlkmaarAZ Alkmaar 2-2 FC Twente | Dutch Eredivisie |
| 12 | Sun 10 May | 64-0 v Sparta RotterdamFC Twente 4-0 Sparta Rotterdam | Dutch Eredivisie |
| 13 | Sun 17 May | 61-5 v PSV EindhovenPSV Eindhoven 5-1 FC Twente | Dutch Eredivisie |
| 14 | Thu 23 Jul | 61-2 v Ferencvárosi TCFC Twente 1-2 Ferencvárosi TC | UEFA Europa League Second Qualifying Round |
| 15 | Thu 30 Jul | 62-2 v Ferencvárosi TCFerencvárosi TC 2-2 FC Twente | UEFA Europa League Second Qualifying Round |
| 16 | Thu 6 Aug | 66-0 v Dunajská StredaFC Twente 6-0 Dunajská Streda | UEFA Conference League Third Qualifying Round |
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