| 1 | Sat 7 Feb | 75-0 v sc HeerenveenFC Twente 5-0 sc Heerenveen | Dutch Eredivisie |
| 2 | Sun 15 Feb | 71-1 v TelstarTelstar 1-1 FC Twente | Dutch Eredivisie |
| 3 | Sun 22 Feb | 72-1 v FC GroningenFC Twente 2-1 FC Groningen | Dutch Eredivisie |
| 4 | Sun 8 Mar | 74-1 v Go Ahead EaglesGo Ahead Eagles 1-4 FC Twente | Dutch Eredivisie |
| 5 | Sun 15 Mar | 70-2 v FC UtrechtFC Twente 0-2 FC Utrecht | Dutch Eredivisie |
| 6 | Sat 21 Mar | 72-1 v Fortuna SittardFortuna Sittard 1-2 FC Twente | Dutch Eredivisie |
| 7 | Sat 4 Apr | 72-1 v AjaxAjax 1-2 FC Twente | Dutch Eredivisie |
| 8 | Fri 10 Apr | 72-1 v VolendamFC Twente 2-1 Volendam | Dutch Eredivisie |
| 9 | Sun 3 May | 72-2 v AZ AlkmaarAZ Alkmaar 2-2 FC Twente | Dutch Eredivisie |
| 10 | Sun 10 May | 74-0 v Sparta RotterdamFC Twente 4-0 Sparta Rotterdam | Dutch Eredivisie |
| 11 | Sun 17 May | 71-5 v PSV EindhovenPSV Eindhoven 5-1 FC Twente | Dutch Eredivisie |
| 12 | Thu 30 Jul | 72-2 v Ferencvárosi TCFerencvárosi TC 2-2 FC Twente | UEFA Europa League Second Qualifying Round |
| 13 | Thu 6 Aug | 76-0 v Dunajská StredaFC Twente 6-0 Dunajská Streda | UEFA Conference League Third Qualifying Round |
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