| 1 | Fri 27 Aug 2021 | 220-1 v MallorcaMallorca 1-0 Espanyol | Spanish La Liga |
| 2 | Sun 12 Sep 2021 | 221-2 v Atlético MadridEspanyol 1-2 Atlético Madrid | Spanish La Liga |
| 3 | Sun 19 Sep 2021 | 22 2-2 v Real BetisReal Betis 2-2 Espanyol | Spanish La Liga |
| 4 | Sat 25 Sep 2021 | 220-2 v SevillaSevilla 2-0 Espanyol | Spanish La Liga |
| 5 | Sun 3 Oct 2021 | 222-1 v Real MadridEspanyol 2-1 Real Madrid | Spanish La Liga |
| 6 | Sat 23 Oct 2021 | 222-2 v ElcheElche 2-2 Espanyol | Spanish La Liga |
| 7 | Tue 26 Oct 2021 | 221-1 v Athletic BilbaoEspanyol 1-1 Athletic Bilbao | Spanish La Liga |
| 8 | Sun 31 Oct 2021 | 221-2 v GetafeGetafe 2-1 Espanyol | Spanish La Liga |
| 9 | Sat 6 Nov 2021 | 222-0 v GranadaEspanyol 2-0 Granada | Spanish La Liga |
| 10 | Sat 20 Nov 2021 | 220-1 v BarcelonaBarcelona 1-0 Espanyol | Spanish La Liga |
| 11 | Sun 28 Nov 2021 | 22 1-0 v Real SociedadEspanyol 1-0 Real Sociedad | Spanish La Liga |
| 12 | Sun 5 Dec 2021 | 22 0-1 v Rayo VallecanoRayo Vallecano 1-0 Espanyol | Spanish La Liga |
| 13 | Sat 11 Dec 2021 | 22 4-3 v LevanteEspanyol 4-3 Levante | Spanish La Liga |
| 14 | Fri 17 Dec 2021 | 221-3 v Celta VigoCelta Vigo 3-1 Espanyol | Spanish La Liga |
| 15 | Fri 31 Dec 2021 | 222-1 v ValenciaValencia 1-2 Espanyol | Spanish La Liga |
| 16 | Mon 10 Jan 2022 | 221-2 v ElcheEspanyol 1-2 Elche | Spanish La Liga |
| 17 | Tue 18 Jan 2022 | 222-2 v CádizCádiz 2-2 Espanyol | Spanish La Liga |
| 18 | Fri 21 Jan 2022 | 221-4 v Real BetisEspanyol 1-4 Real Betis | Spanish La Liga |
| 19 | Sun 13 Feb 2022 | 222-2 v BarcelonaEspanyol 2-2 Barcelona | Spanish La Liga |
| 20 | Sun 20 Feb 2022 | 22 1-1 v SevillaEspanyol 1-1 Sevilla | Spanish La Liga |
| 21 | Sat 5 Mar 2022 | 222-0 v GetafeEspanyol 2-0 Getafe | Spanish La Liga |
| 22 | Sat 12 Mar 2022 | 221-1 v LevanteLevante 1-1 Espanyol | Spanish La Liga |
| 23 | Sun 20 Mar 2022 | 22 1-0 v MallorcaEspanyol 1-0 Mallorca | Spanish La Liga |
| 24 | Mon 4 Apr 2022 | 22 0-1 v Real SociedadReal Sociedad 1-0 Espanyol | Spanish La Liga |
| 25 | Sun 10 Apr 2022 | 221-0 v Celta VigoEspanyol 1-0 Celta Vigo | Spanish La Liga |
| 26 | Sun 17 Apr 2022 | 22 1-2 v Atlético MadridAtlético Madrid 2-1 Espanyol | Spanish La Liga |
| 27 | Thu 21 Apr 2022 | 22 0-1 v Rayo VallecanoEspanyol 0-1 Rayo Vallecano | Spanish La Liga |
| 28 | Sat 30 Apr 2022 | 220-4 v Real MadridReal Madrid 4-0 Espanyol | Spanish La Liga |
| 29 | Sun 8 May 2022 | 221-1 v OsasunaEspanyol 1-1 Osasuna | Spanish La Liga |
| 30 | Wed 11 May 2022 | 22 1-2 v AlavésAlavés 2-1 Espanyol | Spanish La Liga |
| 31 | Sun 22 May 2022 | 220-0 v GranadaGranada 0-0 Espanyol | Spanish La Liga |
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