| 1 | Fri 5 Aug 2022 | 61-6 v Bayern MunichEintracht Frankfurt 1-6 Bayern Munich | German Bundesliga |
| 2 | Sat 13 Aug 2022 | 61-1 v Hertha BerlinHertha Berlin 1-1 Eintracht Frankfurt | German Bundesliga |
| 3 | Sun 21 Aug 2022 | 61-1 v 1 FC KölnEintracht Frankfurt 1-1 1 FC Köln | German Bundesliga |
| 4 | Sun 28 Aug 2022 | 64-3 v Werder BremenWerder Bremen 3-4 Eintracht Frankfurt | German Bundesliga |
| 5 | Sat 3 Sep 2022 | 64-0 v RB LeipzigEintracht Frankfurt 4-0 RB Leipzig | German Bundesliga |
| 6 | Wed 7 Sep 2022 | 6 0-3 v Sporting LisbonEintracht Frankfurt 0-3 Sporting Lisbon | UEFA Champions League Group D |
| 7 | Sat 10 Sep 2022 | 60-1 v VfL WolfsburgEintracht Frankfurt 0-1 VfL Wolfsburg | German Bundesliga |
| 8 | Tue 13 Sep 2022 | 61-0 v MarseilleMarseille 0-1 Eintracht Frankfurt | UEFA Champions League Group D |
| 9 | Sat 17 Sep 2022 | 63-1 v VfB StuttgartVfB Stuttgart 1-3 Eintracht Frankfurt | German Bundesliga |
| 10 | Tue 4 Oct 2022 | 60-0 v Tottenham HotspurEintracht Frankfurt 0-0 Tottenham Hotspur | UEFA Champions League Group D |
| 11 | Sat 8 Oct 2022 | 60-3 v VfL BochumVfL Bochum 3-0 Eintracht Frankfurt | German Bundesliga |
| 12 | Wed 12 Oct 2022 | 62-3 v Tottenham HotspurTottenham Hotspur 3-2 Eintracht Frankfurt | UEFA Champions League Group D |
| 13 | Sat 15 Oct 2022 | 65-1 v Bayer 04 LeverkusenEintracht Frankfurt 5-1 Bayer 04 Leverkusen | German Bundesliga |
| 14 | Sat 22 Oct 2022 | 6 3-1 v Borussia MönchengladbachBorussia Mönchengladbach 1-3 Eintracht Frankfurt | German Bundesliga |
| 15 | Wed 26 Oct 2022 | 62-1 v MarseilleEintracht Frankfurt 2-1 Marseille | UEFA Champions League Group D |
| 16 | Sat 29 Oct 2022 | 61-2 v Borussia DortmundEintracht Frankfurt 1-2 Borussia Dortmund | German Bundesliga |
| 17 | Tue 1 Nov 2022 | 6 2-1 v Sporting LisbonSporting Lisbon 1-2 Eintracht Frankfurt | UEFA Champions League Group D |
| 18 | Sat 5 Nov 2022 | 62-1 v FC AugsburgFC Augsburg 1-2 Eintracht Frankfurt | German Bundesliga |
| 19 | Wed 9 Nov 2022 | 64-2 v 1899 HoffenheimEintracht Frankfurt 4-2 1899 Hoffenheim | German Bundesliga |
| 20 | Sun 13 Nov 2022 | 61-1 v Mainz 05Mainz 05 1-1 Eintracht Frankfurt | German Bundesliga |
| 21 | Sat 21 Jan 2023 | 63-0 v FC Schalke 04Eintracht Frankfurt 3-0 FC Schalke 04 | German Bundesliga |
| 22 | Sat 28 Jan 2023 | 61-1 v Bayern MunichBayern Munich 1-1 Eintracht Frankfurt | German Bundesliga |
| 23 | Sat 4 Feb 2023 | 63-0 v Hertha BerlinEintracht Frankfurt 3-0 Hertha Berlin | German Bundesliga |
| 24 | Sat 18 Feb 2023 | 62-0 v Werder BremenEintracht Frankfurt 2-0 Werder Bremen | German Bundesliga |
| 25 | Tue 21 Feb 2023 | 60-2 v NapoliEintracht Frankfurt 0-2 Napoli | UEFA Champions League Round of 16 |
| 26 | Sat 25 Feb 2023 | 61-2 v RB LeipzigRB Leipzig 2-1 Eintracht Frankfurt | German Bundesliga |
| 27 | Sun 5 Mar 2023 | 6 2-2 v VfL WolfsburgVfL Wolfsburg 2-2 Eintracht Frankfurt | German Bundesliga |
| 28 | Sat 11 Mar 2023 | 61-1 v VfB StuttgartEintracht Frankfurt 1-1 VfB Stuttgart | German Bundesliga |
| 29 | Wed 15 Mar 2023 | 60-3 v NapoliNapoli 3-0 Eintracht Frankfurt | UEFA Champions League Round of 16 |
| 30 | Fri 31 Mar 2023 | 6 1-1 v VfL BochumEintracht Frankfurt 1-1 VfL Bochum | German Bundesliga |
| 31 | Sat 8 Apr 2023 | 6 1-3 v Bayer 04 LeverkusenBayer 04 Leverkusen 3-1 Eintracht Frankfurt | German Bundesliga |
| 32 | Sat 15 Apr 2023 | 61-1 v Borussia MönchengladbachEintracht Frankfurt 1-1 Borussia Mönchengladbach | German Bundesliga |
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