| 1 | Sat 14 Aug 2021 | 72-5 v Borussia DortmundBorussia Dortmund 5-2 Eintracht Frankfurt | German Bundesliga |
| 2 | Sat 21 Aug 2021 | 70-0 v FC AugsburgEintracht Frankfurt 0-0 FC Augsburg | German Bundesliga |
| 3 | Sat 28 Aug 2021 | 7 1-1 v Arminia BielefeldArminia Bielefeld 1-1 Eintracht Frankfurt | German Bundesliga |
| 4 | Sun 12 Sep 2021 | 71-1 v VfB StuttgartEintracht Frankfurt 1-1 VfB Stuttgart | German Bundesliga |
| 5 | Sun 19 Sep 2021 | 71-1 v VfL WolfsburgVfL Wolfsburg 1-1 Eintracht Frankfurt | German Bundesliga |
| 6 | Thu 30 Sep 2021 | 71-0 v Royal AntwerpRoyal Antwerp 0-1 Eintracht Frankfurt | UEFA Europa League Group D |
| 7 | Sun 3 Oct 2021 | 72-1 v Bayern MunichBayern Munich 1-2 Eintracht Frankfurt | German Bundesliga |
| 8 | Sun 24 Oct 2021 | 70-2 v VfL BochumVfL Bochum 2-0 Eintracht Frankfurt | German Bundesliga |
| 9 | Sat 30 Oct 2021 | 71-1 v RB LeipzigEintracht Frankfurt 1-1 RB Leipzig | German Bundesliga |
| 10 | Thu 9 Dec 2021 | 71-1 v FenerbahçeFenerbahçe 1-1 Eintracht Frankfurt | UEFA Europa League Group D |
| 11 | Sat 18 Dec 2021 | 71-0 v Mainz 05Eintracht Frankfurt 1-0 Mainz 05 | German Bundesliga |
| 12 | Sat 8 Jan 2022 | 72-3 v Borussia DortmundEintracht Frankfurt 2-3 Borussia Dortmund | German Bundesliga |
| 13 | Fri 21 Jan 2022 | 70-2 v Arminia BielefeldEintracht Frankfurt 0-2 Arminia Bielefeld | German Bundesliga |
| 14 | Sat 5 Feb 2022 | 73-2 v VfB StuttgartVfB Stuttgart 2-3 Eintracht Frankfurt | German Bundesliga |
| 15 | Sat 12 Feb 2022 | 70-2 v VfL WolfsburgEintracht Frankfurt 0-2 VfL Wolfsburg | German Bundesliga |
| 16 | Sat 26 Feb 2022 | 70-1 v Bayern MunichEintracht Frankfurt 0-1 Bayern Munich | German Bundesliga |
| 17 | Sat 5 Mar 2022 | 74-1 v Hertha BerlinHertha Berlin 1-4 Eintracht Frankfurt | German Bundesliga |
| 18 | Sun 13 Mar 2022 | 72-1 v VfL BochumEintracht Frankfurt 2-1 VfL Bochum | German Bundesliga |
| 19 | Sun 20 Mar 2022 | 7 0-0 v RB LeipzigRB Leipzig 0-0 Eintracht Frankfurt | German Bundesliga |
| 20 | Sun 10 Apr 2022 | 71-2 v SC FreiburgEintracht Frankfurt 1-2 SC Freiburg | German Bundesliga |
| 21 | Thu 14 Apr 2022 | 7 3-2 v BarcelonaBarcelona 2-3 Eintracht Frankfurt | UEFA Europa League Quarter Final |
| 22 | Sun 17 Apr 2022 | 70-2 v 1. FC Union Berlin1. FC Union Berlin 2-0 Eintracht Frankfurt | German Bundesliga |
| 23 | Sat 23 Apr 2022 | 72-2 v 1899 HoffenheimEintracht Frankfurt 2-2 1899 Hoffenheim | German Bundesliga |
| 24 | Mon 2 May 2022 | 70-2 v Bayer 04 LeverkusenBayer 04 Leverkusen 2-0 Eintracht Frankfurt | German Bundesliga |
| 25 | Sun 8 May 2022 | 71-1 v Borussia MönchengladbachEintracht Frankfurt 1-1 Borussia Mönchengladbach | German Bundesliga |
| 26 | Sat 14 May 2022 | 72-2 v Mainz 05Mainz 05 2-2 Eintracht Frankfurt | German Bundesliga |
| 27 | Wed 18 May 2022 | 71-1 v RangersEintracht Frankfurt 1-1 Rangers | UEFA Europa League Final |
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