| 1 | Sat 16 Oct 2021 | 161-4 v Carshalton AthleticCarshalton Athletic 4-1 East Thurrock United | Isthmian League - Premier Division |
| 2 | Tue 19 Oct 2021 | 41-2 v Bishop's StortfordEast Thurrock United 1-2 Bishop's Stortford | Isthmian League - Premier Division |
| 3 | Sat 23 Oct 2021 | 40-8 v Enfield TownEast Thurrock United 0-8 Enfield Town | Isthmian League - Premier Division |
| 4 | Tue 26 Oct 2021 | 40-2 v MargateMargate 2-0 East Thurrock United | Isthmian League - Premier Division |
| 5 | Sat 30 Oct 2021 | 4 0-6 v KingstonianEast Thurrock United 0-6 Kingstonian | Buildbase FA Trophy Third Qualifying Round |
| 6 | Sat 6 Nov 2021 | 40-2 v LeatherheadEast Thurrock United 0-2 Leatherhead | Isthmian League - Premier Division |
| 7 | Sat 20 Nov 2021 | 5 1-1 v Corinthian-CasualsEast Thurrock United 1-1 Corinthian-Casuals | Isthmian League - Premier Division |
| 8 | Sat 27 Nov 2021 | 52-2 v MersthamMerstham 2-2 East Thurrock United | Isthmian League - Premier Division |
| 9 | Sat 4 Dec 2021 | 50-2 v Bowers & PitseaEast Thurrock United 0-2 Bowers & Pitsea | Isthmian League - Premier Division |
| 10 | Wed 15 Dec 2021 | 61-0 v KingstonianKingstonian 0-1 East Thurrock United | Isthmian League - Premier Division |
| 11 | Mon 27 Dec 2021 | 61-2 v Brightlingsea RegentBrightlingsea Regent 2-1 East Thurrock United | Isthmian League - Premier Division |
| 12 | Mon 3 Jan 2022 | 60-5 v Wingate & FinchleyWingate & Finchley 5-0 East Thurrock United | Isthmian League - Premier Division |
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