| 1 | Fri 6 Aug 2021 | 31-1 v Cercle BruggeClub Brugge 1-1 Cercle Brugge | Belgian First Division A |
| 2 | Sun 15 Aug 2021 | 34-0 v SV Zulte WaregemSV Zulte Waregem 0-4 Club Brugge | Belgian First Division A |
| 3 | Sun 22 Aug 2021 | 33-2 v Germinal BeerschotClub Brugge 3-2 Germinal Beerschot | Belgian First Division A |
| 4 | Sun 29 Aug 2021 | 31-6 v KAA GentKAA Gent 6-1 Club Brugge | Belgian First Division A |
| 5 | Fri 10 Sep 2021 | 33-0 v KV OostendeClub Brugge 3-0 KV Oostende | Belgian First Division A |
| 6 | Wed 15 Sep 2021 | 3 1-1 v Paris St GermainClub Brugge 1-1 Paris St Germain | UEFA Champions League Group A |
| 7 | Fri 24 Sep 2021 | 31-1 v Oud-Heverlee LeuvenClub Brugge 1-1 Oud-Heverlee Leuven | Belgian First Division A |
| 8 | Tue 28 Sep 2021 | 3 2-1 v RB LeipzigRB Leipzig 1-2 Club Brugge | UEFA Champions League Group A |
| 9 | Sun 3 Oct 2021 | 3 1-1 v RSC AnderlechtRSC Anderlecht 1-1 Club Brugge | Belgian First Division A |
| 10 | Tue 19 Oct 2021 | 3 1-5 v Manchester CityClub Brugge 1-5 Manchester City | UEFA Champions League Group A |
| 11 | Sun 24 Oct 2021 | 3 1-1 v Royal AntwerpRoyal Antwerp 1-1 Club Brugge | Belgian First Division A |
| 12 | Sat 30 Oct 2021 | 32-1 v Sint-Truidense VVSint-Truidense VV 1-2 Club Brugge | Belgian First Division A |
| 13 | Sun 7 Nov 2021 | 32-2 v Standard LiègeClub Brugge 2-2 Standard Liège | Belgian First Division A |
| 14 | Fri 19 Nov 2021 | 3 1-2 v MechelenMechelen 2-1 Club Brugge | Belgian First Division A |
| 15 | Wed 24 Nov 2021 | 3 0-5 v RB LeipzigClub Brugge 0-5 RB Leipzig | UEFA Champions League Group A |
| 16 | Sun 28 Nov 2021 | 33-2 v KRC GenkKRC Genk 2-3 Club Brugge | Belgian First Division A |
| 17 | Tue 7 Dec 2021 | 31-4 v Paris St GermainParis St Germain 4-1 Club Brugge | UEFA Champions League Group A |
| 18 | Sun 12 Dec 2021 | 33-0 v SV Zulte WaregemClub Brugge 3-0 SV Zulte Waregem | Belgian First Division A |
| 19 | Wed 15 Dec 2021 | 34-1 v Oud-Heverlee LeuvenOud-Heverlee Leuven 1-4 Club Brugge | Belgian First Division A |
| 20 | Sun 19 Dec 2021 | 32-2 v RSC AnderlechtClub Brugge 2-2 RSC Anderlecht | Belgian First Division A |
| 21 | Sun 26 Dec 2021 | 30-2 v Cercle BruggeCercle Brugge 2-0 Club Brugge | Belgian First Division A |
| 22 | Sat 15 Jan 2022 | 32-0 v Sint-Truidense VVClub Brugge 2-0 Sint-Truidense VV | Belgian First Division A |
| 23 | Sun 30 Jan 2022 | 31-0 v KV KortrijkKV Kortrijk 0-1 Club Brugge | Belgian First Division A |
| 24 | Sun 6 Feb 2022 | 3 1-2 v KAA GentClub Brugge 1-2 KAA Gent | Belgian First Division A |
| 25 | Sun 20 Feb 2022 | 33-1 v KAS EupenKAS Eupen 1-3 Club Brugge | Belgian First Division A |
| 26 | Sun 10 Apr 2022 | 32-0 v MechelenClub Brugge 2-0 Mechelen | Belgian First Division A |
| 27 | Sun 24 Apr 2022 | 31-0 v Royal AntwerpClub Brugge 1-0 Royal Antwerp | Belgian First Division A Play-off |
| 28 | Sun 1 May 2022 | 3 0-0 v RSC AnderlechtRSC Anderlecht 0-0 Club Brugge | Belgian First Division A Play-off |
| 29 | Sun 8 May 2022 | 32-0 v Union Saint-GilloiseUnion Saint-Gilloise 0-2 Club Brugge | Belgian First Division A Play-off |
| 30 | Wed 11 May 2022 | 3 1-0 v Union Saint-GilloiseClub Brugge 1-0 Union Saint-Gilloise | Belgian First Division A Play-off |
| 31 | Sun 15 May 2022 | 3 3-1 v Royal AntwerpRoyal Antwerp 1-3 Club Brugge | Belgian First Division A Play-off |
Football Web Pages