| 1 | Mon 2 Jan 2023 | 28 0-5 v Sheffield WednesdaySheffield Wednesday 5-0 Cambridge United | Sky Bet League One |
| 2 | Sat 7 Jan 2023 | 281-2 v Bristol RoversCambridge United 1-2 Bristol Rovers | Sky Bet League One |
| 3 | Sat 21 Jan 2023 | 281-5 v Shrewsbury TownShrewsbury Town 5-1 Cambridge United | Sky Bet League One |
| 4 | Sat 28 Jan 2023 | 280-0 v Lincoln CityLincoln City 0-0 Cambridge United | Sky Bet League One |
| 5 | Sat 4 Feb 2023 | 281-1 v Ipswich TownCambridge United 1-1 Ipswich Town | Sky Bet League One |
| 6 | Sat 11 Feb 2023 | 280-2 v BarnsleyBarnsley 2-0 Cambridge United | Sky Bet League One |
| 7 | Tue 14 Feb 2023 | 281-2 v Cheltenham TownCambridge United 1-2 Cheltenham Town | Sky Bet League One |
| 8 | Sat 18 Feb 2023 | 28 1-0 v Oxford UnitedCambridge United 1-0 Oxford United | Sky Bet League One |
| 9 | Tue 21 Feb 2023 | 28 0-1 v Fleetwood TownFleetwood Town 1-0 Cambridge United | Sky Bet League One |
| 10 | Sat 25 Feb 2023 | 280-2 v Exeter CityExeter City 2-0 Cambridge United | Sky Bet League One |
| 11 | Sat 4 Mar 2023 | 280-1 v PortsmouthCambridge United 0-1 Portsmouth | Sky Bet League One |
| 12 | Tue 7 Mar 2023 | 281-1 v MorecambeCambridge United 1-1 Morecambe | Sky Bet League One |
| 13 | Sat 11 Mar 2023 | 280-1 v Milton Keynes DonsMilton Keynes Dons 1-0 Cambridge United | Sky Bet League One |
| 14 | Sat 18 Mar 2023 | 281-2 v Charlton AthleticCambridge United 1-2 Charlton Athletic | Sky Bet League One |
| 15 | Sat 1 Apr 2023 | 282-0 v Port ValePort Vale 0-2 Cambridge United | Sky Bet League One |
| 16 | Fri 7 Apr 2023 | 282-1 v Fleetwood TownCambridge United 2-1 Fleetwood Town | Sky Bet League One |
| 17 | Mon 10 Apr 2023 | 281-1 v Bolton WanderersBolton Wanderers 1-1 Cambridge United | Sky Bet League One |
| 18 | Sat 15 Apr 2023 | 282-0 v Peterborough UnitedCambridge United 2-0 Peterborough United | Sky Bet League One |
| 19 | Tue 18 Apr 2023 | 281-2 v Wycombe WanderersCambridge United 1-2 Wycombe Wanderers | Sky Bet League One |
| 20 | Sat 22 Apr 2023 | 28 1-3 v Plymouth ArgylePlymouth Argyle 3-1 Cambridge United | Sky Bet League One |
| 21 | Sat 29 Apr 2023 | 282-1 v Accrington StanleyAccrington Stanley 1-2 Cambridge United | Sky Bet League One |
| 22 | Wed 3 May 2023 | 280-1 v Burton AlbionBurton Albion 1-0 Cambridge United | Sky Bet League One |
| 23 | Sun 7 May 2023 | 282-0 v Forest Green RoversCambridge United 2-0 Forest Green Rovers | Sky Bet League One |
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