| 1 | Sat 27 Aug 2022 | 61-0 v Hertha BerlinHertha Berlin 0-1 Borussia Dortmund | German Bundesliga |
| 2 | Fri 2 Sep 2022 | 61-0 v 1899 HoffenheimBorussia Dortmund 1-0 1899 Hoffenheim | German Bundesliga |
| 3 | Tue 6 Sep 2022 | 63-0 v FC CopenhagenBorussia Dortmund 3-0 FC Copenhagen | UEFA Champions League Group G |
| 4 | Sat 10 Sep 2022 | 60-3 v RB LeipzigRB Leipzig 3-0 Borussia Dortmund | German Bundesliga |
| 5 | Wed 14 Sep 2022 | 6 1-2 v Manchester CityManchester City 2-1 Borussia Dortmund | UEFA Champions League Group G |
| 6 | Sat 17 Sep 2022 | 61-0 v FC Schalke 04Borussia Dortmund 1-0 FC Schalke 04 | German Bundesliga |
| 7 | Sat 1 Oct 2022 | 62-3 v 1 FC Köln1 FC Köln 3-2 Borussia Dortmund | German Bundesliga |
| 8 | Wed 5 Oct 2022 | 6 4-1 v SevillaSevilla 1-4 Borussia Dortmund | UEFA Champions League Group G |
| 9 | Sat 8 Oct 2022 | 62-2 v Bayern MunichBorussia Dortmund 2-2 Bayern Munich | German Bundesliga |
| 10 | Tue 11 Oct 2022 | 6 1-1 v SevillaBorussia Dortmund 1-1 Sevilla | UEFA Champions League Group G |
| 11 | Sun 16 Oct 2022 | 6 0-2 v 1 FC Union Berlin1 FC Union Berlin 2-0 Borussia Dortmund | German Bundesliga |
| 12 | Sat 22 Oct 2022 | 6 5-0 v VfB StuttgartBorussia Dortmund 5-0 VfB Stuttgart | German Bundesliga |
| 13 | Sat 29 Oct 2022 | 6 2-1 v Eintracht FrankfurtEintracht Frankfurt 1-2 Borussia Dortmund | German Bundesliga |
| 14 | Wed 2 Nov 2022 | 61-1 v FC CopenhagenFC Copenhagen 1-1 Borussia Dortmund | UEFA Champions League Group G |
| 15 | Sat 5 Nov 2022 | 6 3-0 v VfL BochumBorussia Dortmund 3-0 VfL Bochum | German Bundesliga |
| 16 | Tue 8 Nov 2022 | 60-2 v VfL WolfsburgVfL Wolfsburg 2-0 Borussia Dortmund | German Bundesliga |
| 17 | Fri 11 Nov 2022 | 62-4 v Borussia MönchengladbachBorussia Mönchengladbach 4-2 Borussia Dortmund | German Bundesliga |
| 18 | Sun 22 Jan 2023 | 64-3 v FC AugsburgBorussia Dortmund 4-3 FC Augsburg | German Bundesliga |
| 19 | Wed 25 Jan 2023 | 62-1 v Mainz 05Mainz 05 1-2 Borussia Dortmund | German Bundesliga |
| 20 | Sun 29 Jan 2023 | 6 2-0 v Bayer 04 LeverkusenBayer 04 Leverkusen 0-2 Borussia Dortmund | German Bundesliga |
| 21 | Sat 11 Feb 2023 | 62-0 v Werder BremenWerder Bremen 0-2 Borussia Dortmund | German Bundesliga |
| 22 | Wed 15 Feb 2023 | 6 1-0 v ChelseaBorussia Dortmund 1-0 Chelsea | UEFA Champions League Round of 16 |
| 23 | Sun 19 Feb 2023 | 64-1 v Hertha BerlinBorussia Dortmund 4-1 Hertha Berlin | German Bundesliga |
| 24 | Sat 25 Feb 2023 | 61-0 v 1899 Hoffenheim1899 Hoffenheim 0-1 Borussia Dortmund | German Bundesliga |
| 25 | Fri 3 Mar 2023 | 6 2-1 v RB LeipzigBorussia Dortmund 2-1 RB Leipzig | German Bundesliga |
| 26 | Tue 7 Mar 2023 | 60-2 v ChelseaChelsea 2-0 Borussia Dortmund | UEFA Champions League Round of 16 |
| 27 | Sat 1 Apr 2023 | 62-4 v Bayern MunichBayern Munich 4-2 Borussia Dortmund | German Bundesliga |
| 28 | Sat 8 Apr 2023 | 62-1 v 1 FC Union BerlinBorussia Dortmund 2-1 1 FC Union Berlin | German Bundesliga |
| 29 | Sat 15 Apr 2023 | 63-3 v VfB StuttgartVfB Stuttgart 3-3 Borussia Dortmund | German Bundesliga |
| 30 | Sat 22 Apr 2023 | 64-0 v Eintracht FrankfurtBorussia Dortmund 4-0 Eintracht Frankfurt | German Bundesliga |
| 31 | Sun 7 May 2023 | 66-0 v VfL WolfsburgBorussia Dortmund 6-0 VfL Wolfsburg | German Bundesliga |
| 32 | Sat 13 May 2023 | 65-2 v Borussia MönchengladbachBorussia Dortmund 5-2 Borussia Mönchengladbach | German Bundesliga |
| 33 | Sun 21 May 2023 | 63-0 v FC AugsburgFC Augsburg 0-3 Borussia Dortmund | German Bundesliga |
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