| 1 | Sat 3 Aug 2024 | 62-3 v JarrowBillingham Synthonia 2-3 Jarrow | Northern League Division Two |
| 2 | Tue 6 Aug 2024 | 47-1 v Sunderland RCABillingham Synthonia 7-1 Sunderland RCA | Northern League Division Two |
| 3 | Tue 13 Aug 2024 | 83-0 v Darlington TownBillingham Synthonia 3-0 Darlington Town | Northern League Division Two |
| 4 | Fri 16 Aug 2024 | 81-0 v Billingham TownBillingham Synthonia 1-0 Billingham Town | Northern League Division Two |
| 5 | Tue 20 Aug 2024 | 80-1 v Chester-le-Street TownChester-le-Street Town 1-0 Billingham Synthonia | Northern League Division Two |
| 6 | Tue 27 Aug 2024 | 112-3 v Sunderland West EndBillingham Synthonia 2-3 Sunderland West End | Northern League Division Two |
| 7 | Tue 3 Sep 2024 | 21-2 v Chester-le-Street UnitedBillingham Synthonia 1-2 Chester-le-Street United | Northern League Division Two |
| 8 | Fri 6 Sep 2024 | 25-0 v Grangetown Boys ClubGrangetown Boys Club 0-5 Billingham Synthonia | Northern League Division Two |
| 9 | Sat 14 Sep 2024 | 144-1 v WashingtonWashington 1-4 Billingham Synthonia | Northern League Division Two |
| 10 | Wed 18 Sep 2024 | 8 0-1 v ThornabyThornaby 1-0 Billingham Synthonia | Northern League Division Two |
| 11 | Sat 21 Sep 2024 | 100-2 v Campion AFCCampion AFC 2-0 Billingham Synthonia | Isuzu FA Vase Second Qualifying Round |
| 12 | Tue 24 Sep 2024 | 70-3 v FC HartlepoolBillingham Synthonia 0-3 FC Hartlepool | Northern League Division Two |
| 13 | Sat 28 Sep 2024 | 80-2 v Boldon Community AssociationBoldon Community Association 2-0 Billingham Synthonia | Northern League Division Two |
| 14 | Wed 13 Nov 2024 | 163-0 v Yarm & EaglescliffeBillingham Synthonia 3-0 Yarm & Eaglescliffe | Northern League Division Two |
| 15 | Sat 16 Nov 2024 | 160-0 v Sunderland RCASunderland RCA 0-0 Billingham Synthonia | Northern League Division Two |
| 16 | Sat 30 Nov 2024 | 140-1 v Chester-le-Street TownBillingham Synthonia 0-1 Chester-le-Street Town | Northern League Division Two |
| 17 | Sat 14 Dec 2024 | 82-0 v Newcastle UniversityBillingham Synthonia 2-0 Newcastle University | Northern League Division Two |
| 18 | Sat 21 Dec 2024 | 8 4-2 v Ryton & Crawcrook AlbionBillingham Synthonia 4-2 Ryton & Crawcrook Albion | Northern League Division Two |
| 19 | Sat 11 Jan 2025 | 82-0 v Bedlington TerriersBillingham Synthonia 2-0 Bedlington Terriers | Northern League Division Two |
| 20 | Sat 18 Jan 2025 | 81-3 v JarrowJarrow 3-1 Billingham Synthonia | Northern League Division Two |
| 21 | Wed 22 Jan 2025 | 8 1-1 v Darlington TownDarlington Town 1-1 Billingham Synthonia | Northern League Division Two |
| 22 | Fri 31 Jan 2025 | 83-3 v Billingham TownBillingham Town 3-3 Billingham Synthonia | Northern League Division Two |
| 23 | Tue 4 Feb 2025 | 81-0 v FC HartlepoolFC Hartlepool 0-1 Billingham Synthonia | Northern League Division Two |
| 24 | Sat 22 Feb 2025 | 122-0 v WashingtonBillingham Synthonia 2-0 Washington | Northern League Division Two |
| 25 | Sat 1 Mar 2025 | 81-2 v Sunderland West EndSunderland West End 2-1 Billingham Synthonia | Northern League Division Two |
| 26 | Sat 15 Mar 2025 | 151-3 v Redcar TownBillingham Synthonia 1-3 Redcar Town | Northern League Division Two |
| 27 | Sat 22 Mar 2025 | 8 1-3 v PrudhoePrudhoe 3-1 Billingham Synthonia | Northern League Division Two |
| 28 | Sat 12 Apr 2025 | 104-0 v Esh WinningBillingham Synthonia 4-0 Esh Winning | Northern League Division Two |
| 29 | Fri 18 Apr 2025 | 145-2 v Horden Community WelfareBillingham Synthonia 5-2 Horden Community Welfare | Northern League Division Two |
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