| 1 | Sat 23 Aug | 141-2 v TSG HoffenheimBayer Leverkusen 1-2 TSG Hoffenheim | German Bundesliga |
| 2 | Sat 30 Aug | 143-3 v Werder BremenWerder Bremen 3-3 Bayer Leverkusen | German Bundesliga |
| 3 | Fri 12 Sep | 143-1 v Eintracht FrankfurtBayer Leverkusen 3-1 Eintracht Frankfurt | German Bundesliga |
| 4 | Thu 18 Sep | 142-2 v FC CopenhagenFC Copenhagen 2-2 Bayer Leverkusen | UEFA Champions League Matchday 1 |
| 5 | Sun 21 Sep | 141-1 v Borussia MönchengladbachBayer Leverkusen 1-1 Borussia Mönchengladbach | German Bundesliga |
| 6 | Sat 27 Sep | 142-1 v FC St PauliFC St Pauli 1-2 Bayer Leverkusen | German Bundesliga |
| 7 | Sun 26 Oct | 142-0 v SC FreiburgBayer Leverkusen 2-0 SC Freiburg | German Bundesliga |
| 8 | Sat 1 Nov | 140-3 v Bayern MunichBayern Munich 3-0 Bayer Leverkusen | German Bundesliga |
| 9 | Wed 5 Nov | 141-0 v BenficaBenfica 0-1 Bayer Leverkusen | UEFA Champions League Matchday 4 |
| 10 | Sat 8 Nov | 146-0 v 1 FC HeidenheimBayer Leverkusen 6-0 1 FC Heidenheim | German Bundesliga |
| 11 | Sat 22 Nov | 143-1 v VfL WolfsburgVfL Wolfsburg 1-3 Bayer Leverkusen | German Bundesliga |
| 12 | Tue 25 Nov | 142-0 v Manchester CityManchester City 0-2 Bayer Leverkusen | UEFA Champions League Matchday 5 |
| 13 | Sat 29 Nov | 141-2 v Borussia DortmundBayer Leverkusen 1-2 Borussia Dortmund | German Bundesliga |
| 14 | Sat 6 Dec | 140-2 v FC AugsburgFC Augsburg 2-0 Bayer Leverkusen | German Bundesliga |
| 15 | Wed 10 Dec | 142-2 v Newcastle UnitedBayer Leverkusen 2-2 Newcastle United | UEFA Champions League Matchday 6 |
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