| 1 | Sat 6 Feb 2021 | 285-2 v VfB StuttgartBayer 04 Leverkusen 5-2 VfB Stuttgart | German Bundesliga |
| 2 | Sat 13 Feb 2021 | 282-2 v Mainz 05Bayer 04 Leverkusen 2-2 Mainz 05 | German Bundesliga |
| 3 | Thu 18 Feb 2021 | 283-4 v Young BoysYoung Boys 4-3 Bayer 04 Leverkusen | Europa League Round of 32 |
| 4 | Sun 21 Feb 2021 | 281-1 v FC AugsburgFC Augsburg 1-1 Bayer 04 Leverkusen | German Bundesliga |
| 5 | Thu 25 Feb 2021 | 280-2 v Young BoysBayer 04 Leverkusen 0-2 Young Boys | Europa League Round of 32 |
| 6 | Sun 28 Feb 2021 | 281-2 v SC FreiburgBayer 04 Leverkusen 1-2 SC Freiburg | German Bundesliga |
| 7 | Sat 6 Mar 2021 | 281-0 v Borussia MönchengladbachBorussia Mönchengladbach 0-1 Bayer 04 Leverkusen | German Bundesliga |
| 8 | Sun 14 Mar 2021 | 281-2 v Arminia BielefeldBayer 04 Leverkusen 1-2 Arminia Bielefeld | German Bundesliga |
| 9 | Sun 21 Mar 2021 | 280-3 v Hertha BerlinHertha Berlin 3-0 Bayer 04 Leverkusen | German Bundesliga |
| 10 | Sat 8 May 2021 | 280-0 v Werder BremenWerder Bremen 0-0 Bayer 04 Leverkusen | German Bundesliga |
| 11 | Sat 15 May 2021 | 281-1 v 1. FC Union BerlinBayer 04 Leverkusen 1-1 1. FC Union Berlin | German Bundesliga |
| 12 | Sat 22 May 2021 | 281-3 v Borussia DortmundBorussia Dortmund 3-1 Bayer 04 Leverkusen | German Bundesliga |
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