| 1 | Tue 25 Jan 2022 | 330-3 v Nottingham ForestNottingham Forest 3-0 Barnsley | Sky Bet Championship |
| 2 | Sat 29 Jan 2022 | 330-1 v AFC BournemouthBarnsley 0-1 AFC Bournemouth | Sky Bet Championship |
| 3 | Tue 22 Feb 2022 | 332-0 v Hull CityHull City 0-2 Barnsley | Sky Bet Championship |
| 4 | Sat 26 Feb 2022 | 333-2 v MiddlesbroughBarnsley 3-2 Middlesbrough | Sky Bet Championship |
| 5 | Sat 5 Mar 2022 | 33 0-2 v Derby CountyDerby County 2-0 Barnsley | Sky Bet Championship |
| 6 | Tue 8 Mar 2022 | 331-1 v Stoke CityBarnsley 1-1 Stoke City | Sky Bet Championship |
| 7 | Sat 12 Mar 2022 | 33 1-1 v FulhamBarnsley 1-1 Fulham | Sky Bet Championship |
| 8 | Tue 15 Mar 2022 | 332-0 v Bristol CityBarnsley 2-0 Bristol City | Sky Bet Championship |
| 9 | Sat 19 Mar 2022 | 330-2 v Sheffield UnitedSheffield United 2-0 Barnsley | Sky Bet Championship |
| 10 | Sat 2 Apr 2022 | 331-1 v ReadingBarnsley 1-1 Reading | Sky Bet Championship |
| 11 | Fri 15 Apr 2022 | 33 1-1 v Swansea CitySwansea City 1-1 Barnsley | Sky Bet Championship |
| 12 | Mon 18 Apr 2022 | 330-2 v Peterborough UnitedBarnsley 0-2 Peterborough United | Sky Bet Championship |
| 13 | Fri 22 Apr 2022 | 33 1-2 v Huddersfield TownHuddersfield Town 2-1 Barnsley | Sky Bet Championship |
| 14 | Tue 26 Apr 2022 | 330-2 v BlackpoolBarnsley 0-2 Blackpool | Sky Bet Championship |
| 15 | Sat 30 Apr 2022 | 331-3 v Preston North EndBarnsley 1-3 Preston North End | Sky Bet Championship |
| 16 | Sat 7 May 2022 | 33 0-4 v West Bromwich AlbionWest Bromwich Albion 4-0 Barnsley | Sky Bet Championship |
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