| 1 | Tue 2 Nov 2021 | 71-0 v Dynamo KievDynamo Kiev 0-1 Barcelona | UEFA Champions League Group E |
| 2 | Tue 23 Nov 2021 | 70-0 v BenficaBarcelona 0-0 Benfica | UEFA Champions League Group E |
| 3 | Sat 27 Nov 2021 | 73-1 v VillarrealVillarreal 1-3 Barcelona | Spanish La Liga |
| 4 | Sat 4 Dec 2021 | 70-1 v Real BetisBarcelona 0-1 Real Betis | Spanish La Liga |
| 5 | Wed 8 Dec 2021 | 70-3 v Bayern MunichBayern Munich 3-0 Barcelona | UEFA Champions League Group E |
| 6 | Sun 12 Dec 2021 | 72-2 v OsasunaOsasuna 2-2 Barcelona | Spanish La Liga |
| 7 | Sat 18 Dec 2021 | 73-2 v ElcheBarcelona 3-2 Elche | Spanish La Liga |
| 8 | Tue 21 Dec 2021 | 71-1 v SevillaSevilla 1-1 Barcelona | Spanish La Liga |
| 9 | Sat 8 Jan 2022 | 71-1 v GranadaGranada 1-1 Barcelona | Spanish La Liga |
| 10 | Sun 13 Feb 2022 | 72-2 v EspanyolEspanyol 2-2 Barcelona | Spanish La Liga |
| 11 | Thu 17 Feb 2022 | 71-1 v NapoliBarcelona 1-1 Napoli | UEFA Europa League Round of 32 |
| 12 | Sun 20 Feb 2022 | 74-1 v ValenciaValencia 1-4 Barcelona | Spanish La Liga |
| 13 | Thu 24 Feb 2022 | 74-2 v NapoliNapoli 2-4 Barcelona | UEFA Europa League Round of 32 |
| 14 | Sun 27 Feb 2022 | 74-0 v Athletic BilbaoBarcelona 4-0 Athletic Bilbao | Spanish La Liga |
| 15 | Sun 6 Mar 2022 | 7 2-1 v ElcheElche 1-2 Barcelona | Spanish La Liga |
| 16 | Thu 10 Mar 2022 | 70-0 v GalatasarayBarcelona 0-0 Galatasaray | UEFA Europa League Round of 16 |
| 17 | Sun 13 Mar 2022 | 74-0 v OsasunaBarcelona 4-0 Osasuna | Spanish La Liga |
| 18 | Thu 17 Mar 2022 | 72-1 v GalatasarayGalatasaray 1-2 Barcelona | UEFA Europa League Round of 16 |
| 19 | Sun 20 Mar 2022 | 74-0 v Real MadridReal Madrid 0-4 Barcelona | Spanish La Liga |
| 20 | Sun 3 Apr 2022 | 7 1-0 v SevillaBarcelona 1-0 Sevilla | Spanish La Liga |
| 21 | Thu 7 Apr 2022 | 71-1 v Eintracht FrankfurtEintracht Frankfurt 1-1 Barcelona | UEFA Europa League Quarter Final |
| 22 | Sun 10 Apr 2022 | 73-2 v LevanteLevante 2-3 Barcelona | Spanish La Liga |
| 23 | Thu 14 Apr 2022 | 7 2-3 v Eintracht FrankfurtBarcelona 2-3 Eintracht Frankfurt | UEFA Europa League Quarter Final |
| 24 | Mon 18 Apr 2022 | 70-1 v CádizBarcelona 0-1 Cádiz | Spanish La Liga |
| 25 | Thu 21 Apr 2022 | 71-0 v Real SociedadReal Sociedad 0-1 Barcelona | Spanish La Liga |
| 26 | Sun 24 Apr 2022 | 7 0-1 v Rayo VallecanoBarcelona 0-1 Rayo Vallecano | Spanish La Liga |
| 27 | Sun 1 May 2022 | 72-1 v MallorcaBarcelona 2-1 Mallorca | Spanish La Liga |
| 28 | Sat 7 May 2022 | 72-1 v Real BetisReal Betis 1-2 Barcelona | Spanish La Liga |
| 29 | Tue 10 May 2022 | 73-1 v Celta VigoBarcelona 3-1 Celta Vigo | Spanish La Liga |
| 30 | Sun 22 May 2022 | 70-2 v VillarrealBarcelona 0-2 Villarreal | Spanish La Liga |
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