| 1 | Sun 15 Aug 2021 | 152-1 v Celta VigoCelta Vigo 1-2 Atlético Madrid | Spanish La Liga |
| 2 | Sun 22 Aug 2021 | 151-0 v ElcheAtlético Madrid 1-0 Elche | Spanish La Liga |
| 3 | Sun 29 Aug 2021 | 152-2 v VillarrealAtlético Madrid 2-2 Villarreal | Spanish La Liga |
| 4 | Sun 12 Sep 2021 | 152-1 v EspanyolEspanyol 1-2 Atlético Madrid | Spanish La Liga |
| 5 | Sat 18 Sep 2021 | 15 0-0 v Athletic BilbaoAtlético Madrid 0-0 Athletic Bilbao | Spanish La Liga |
| 6 | Tue 21 Sep 2021 | 152-1 v GetafeGetafe 1-2 Atlético Madrid | Spanish La Liga |
| 7 | Sat 25 Sep 2021 | 15 0-1 v AlavésAlavés 1-0 Atlético Madrid | Spanish La Liga |
| 8 | Sat 2 Oct 2021 | 152-0 v BarcelonaAtlético Madrid 2-0 Barcelona | Spanish La Liga |
| 9 | Sun 31 Oct 2021 | 153-0 v Real BetisAtlético Madrid 3-0 Real Betis | Spanish La Liga |
| 10 | Sun 7 Nov 2021 | 153-3 v ValenciaValencia 3-3 Atlético Madrid | Spanish La Liga |
| 11 | Sat 20 Nov 2021 | 151-0 v OsasunaAtlético Madrid 1-0 Osasuna | Spanish La Liga |
| 12 | Wed 24 Nov 2021 | 15 0-1 v AC MilanAtlético Madrid 0-1 AC Milan | UEFA Champions League Group B |
| 13 | Sun 28 Nov 2021 | 154-1 v CádizCádiz 1-4 Atlético Madrid | Spanish La Liga |
| 14 | Sat 4 Dec 2021 | 151-2 v MallorcaAtlético Madrid 1-2 Mallorca | Spanish La Liga |
| 15 | Sun 6 Feb 2022 | 152-4 v BarcelonaBarcelona 4-2 Atlético Madrid | Spanish La Liga |
| 16 | Sat 12 Feb 2022 | 15 4-3 v GetafeAtlético Madrid 4-3 Getafe | Spanish La Liga |
| 17 | Wed 16 Feb 2022 | 15 0-1 v LevanteAtlético Madrid 0-1 Levante | Spanish La Liga |
| 18 | Sat 19 Feb 2022 | 153-0 v OsasunaOsasuna 0-3 Atlético Madrid | Spanish La Liga |
| 19 | Wed 23 Feb 2022 | 151-1 v Manchester UnitedAtlético Madrid 1-1 Manchester United | UEFA Champions League Round of 16 |
| 20 | Sat 26 Feb 2022 | 15 2-0 v Celta VigoAtlético Madrid 2-0 Celta Vigo | Spanish La Liga |
| 21 | Fri 11 Mar 2022 | 15 2-1 v CádizAtlético Madrid 2-1 Cádiz | Spanish La Liga |
| 22 | Tue 15 Mar 2022 | 151-0 v Manchester UnitedManchester United 0-1 Atlético Madrid | UEFA Champions League Round of 16 |
| 23 | Sat 19 Mar 2022 | 15 1-0 v Rayo VallecanoRayo Vallecano 0-1 Atlético Madrid | Spanish La Liga |
| 24 | Sat 2 Apr 2022 | 154-1 v AlavésAtlético Madrid 4-1 Alavés | Spanish La Liga |
| 25 | Tue 5 Apr 2022 | 150-1 v Manchester CityManchester City 1-0 Atlético Madrid | UEFA Champions League Quarter Final |
| 26 | Sat 9 Apr 2022 | 15 0-1 v MallorcaMallorca 1-0 Atlético Madrid | Spanish La Liga |
| 27 | Wed 13 Apr 2022 | 15 0-0 v Manchester CityAtlético Madrid 0-0 Manchester City | UEFA Champions League Quarter Final |
| 28 | Sun 17 Apr 2022 | 15 2-1 v EspanyolAtlético Madrid 2-1 Espanyol | Spanish La Liga |
| 29 | Wed 20 Apr 2022 | 15 0-0 v GranadaAtlético Madrid 0-0 Granada | Spanish La Liga |
| 30 | Sun 8 May 2022 | 15 1-0 v Real MadridAtlético Madrid 1-0 Real Madrid | Spanish La Liga |
| 31 | Wed 11 May 2022 | 152-0 v ElcheElche 0-2 Atlético Madrid | Spanish La Liga |
| 32 | Sun 15 May 2022 | 151-1 v SevillaAtlético Madrid 1-1 Sevilla | Spanish La Liga |
| 33 | Sun 22 May 2022 | 15 2-1 v Real SociedadReal Sociedad 1-2 Atlético Madrid | Spanish La Liga |
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